Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 11/20 | 0.45 |
| ▸ | CA2 | P00918 | 11/20 | 0.45 |
| ▸ | CA12 | O43570 | 10/20 | 0.45 |
| ▸ | CA5A | P35218 | 10/20 | 0.45 |
| ▸ | CA5B | Q9Y2D0 | 9/20 | 0.45 |
| ▸ | CA4 | P22748 | 8/20 | 0.45 |
| ▸ | CA7 | P43166 | 8/20 | 0.45 |
| ▸ | CA9 | Q16790 | 4/20 | 0.45 |
| ▸ | CA6 | P23280 | 2/20 | 0.45 |
| ▸ | CA13 | Q8N1Q1 | 2/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.45 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.42 |
| ▸ | FYN | P06241 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.42 |
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9007984 | 1.00 | TSHR (0.55) | TSHRPTPN1CA1CA2CA12 | |
| SCHEMBL6207548 | 0.84 | TSHR (0.50) | TSHRPTPN1CA1CA2CA12 | |
| SCHEMBL9007978 | 0.81 | TSHR (0.69) | TSHRPTPN1CA1CA2CA12 | |
| SCHEMBL9007982 | 0.81 | TSHR (0.69) | TSHRPTPN1CA1CA2CA12 | |
| SCHEMBL8946081 | 0.81 | TSHR (0.47) | TSHRPTPN1CA1CA2CA12 | |
| SCHEMBL3841982 | 0.81 | TSHR (0.47) | TSHRPTPN1CA1CA2CA12 | |
| SCHEMBL9008057 | 0.78 | TSHR (0.60) | TSHRPTPN1CA1CA2CA12 | |
| SCHEMBL9008049 | 0.78 | TSHR (0.60) | TSHRPTPN1CA1CA2CA12 | |
| SCHEMBL8946221 | 0.75 | HSD17B10 (0.47) | TSHRCA1CA2CA12CA5A | |
| SCHEMBL7051328 | 0.74 | LMNA (0.54) | TSHRCA1CA2CA12CA5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0511917-B1 | Glycosylated prodrugs, process for their preparation and uses thereof | HOECHST SA LAB (FR) | 1996-10-23 | — | — | EP | claimed |
| WO-1992019639-A1 | GLYCOSYLATED PRODRUGS, METHOD OF PREPARATION AND USE | LABORATOIRES HOECHST (FR) | 1992-11-12 | — | — | WO | claimed |
| EP-0511917-A1 | Glycosylated prodrugs, process for their preparation and uses thereof | LABORATOIRES HOECHST S.A. (FR) | 1992-11-04 | — | — | EP | claimed |
| EP-0511917-B1 | Glycosylated prodrugs, process for their preparation and uses thereof | HOECHST SA LAB (FR) | 1996-10-23 | — | — | EP | disclosed |
| WO-1992019639-A1 | GLYCOSYLATED PRODRUGS, METHOD OF PREPARATION AND USE | LABORATOIRES HOECHST (FR) | 1992-11-12 | — | — | WO | disclosed |
| EP-0511917-A1 | Glycosylated prodrugs, process for their preparation and uses thereof | LABORATOIRES HOECHST S.A. (FR) | 1992-11-04 | — | — | EP | disclosed |