Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3A | P49840 | 1/20 | 0.46 |
| ▸ | GSK3B | P49841 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 11/20 | 0.42 |
| ▸ | PPARA | Q07869 | 8/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | PPARD | Q03181 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9787633 | 0.86 | HDAC1 (0.44) | GSK3AGSK3BHDAC1HDAC6KDM4E | |
| SCHEMBL9008046 | 0.83 | GSK3A (0.46) | GSK3AGSK3BKDM4EPPARGPPARA | |
| SCHEMBL8650155 | 0.80 | FFAR1 (0.57) | GSK3AGSK3BFFAR1PPARGPPARA | |
| SCHEMBL13960286 | 0.79 | KDM4E (0.55) | FFAR1KDM4EPPARGPPARAPPARD | |
| SCHEMBL13938032 | 0.79 | S1PR1 (0.56) | — | |
| SCHEMBL9008074 | 0.78 | GSK3A (0.41) | GSK3AGSK3BPPARGPPARAHRH3 | |
| SCHEMBL9128417 | 0.78 | FFAR1 (0.67) | FFAR1KDM4EPPARGPPARAHPGD | |
| SCHEMBL14373654 | 0.78 | KDM4E (0.59) | FFAR1KDM4EPPARGPPARAHRH3 | |
| SCHEMBL7489196 | 0.77 | FFAR1 (0.50) | FFAR1KDM4EPPARGPPARAPPARD | |
| SCHEMBL7879558 | 0.76 | KDM4E (0.56) | FFAR1KDM4EPPARGPPARAHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5512689-A | TREATING A STARTING KETONE WITH A BORANE REDUCING AGENT IN THE PRESENCE OF A CHIRAL OXAZABOROLIDINE CATLAYST, PRODUCT FREE OF ENANTIMERS | PFIZER INC. (US) | 1996-04-30 | — | — | US | disclosed |