Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOAT1 | P35610 | 6/20 | 0.36 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9008152 | 0.97 | SOAT1 (0.36) | SOAT1NR1I2KDM4E | |
| SCHEMBL9008090 | 0.96 | SOAT1 (0.35) | SOAT1NR1I2KDM4E | |
| SCHEMBL9008067 | 0.96 | SOAT1 (0.35) | SOAT1NR1I2KDM4E | |
| SCHEMBL9008139 | 0.96 | SOAT1 (0.35) | SOAT1NR1I2KDM4E | |
| SCHEMBL9008269 | 0.92 | SOAT1 (0.39) | SOAT1 | |
| SCHEMBL9008128 | 0.88 | SOAT1 (0.36) | SOAT1 | |
| SCHEMBL9008145 | 0.87 | DDAH1 (0.35) | SOAT1SMN1; SMN2 | |
| SCHEMBL13716530 | 0.80 | SOAT1 (0.36) | SOAT1 | |
| SCHEMBL9008080 | 0.77 | SOAT1 (0.35) | SOAT1 | |
| SCHEMBL13716586 | 0.77 | SOAT1 (0.35) | SOAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5491152-A | Derivatives of cyclic ethers and sulfides for the treatment of atherosclerosis | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1996-02-13 | — | — | US | disclosed |