Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9008205 | 1.00 | GAA (0.32) | GAA | |
| SCHEMBL5682292 | 0.84 | GBA1 (0.33) | GAA | |
| SCHEMBL9008126 | 0.72 | LMNA (0.34) | — | |
| SCHEMBL9151028 | 0.70 | MANBA (0.31) | — | |
| SCHEMBL9151038 | 0.70 | MANBA (0.31) | — | |
| SCHEMBL10822077 | 0.70 | LMNA (0.34) | — | |
| SCHEMBL7439913 | 0.70 | LMNA (0.34) | — | |
| SCHEMBL16149343 | 0.63 | — | — | |
| SCHEMBL30750891 | 0.61 | GAA (0.33) | GAA | |
| SCHEMBL18870141 | 0.60 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5491152-A | Derivatives of cyclic ethers and sulfides for the treatment of atherosclerosis | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1996-02-13 | — | — | US | disclosed |