Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Propionic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.59 |
| ▸ | CA1 | P00915 | 3/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 4/20 | 0.38 |
| ▸ | GMNN | O75496 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 3/20 | 0.36 |
| ▸ | FABP3 | P05413 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Zinc Ion SCHEMBL969200 | 0.91 | EPHX1 (0.65) | EPHX1CA1CA2CES2GMNN | |
| Zinc Ion SCHEMBL967036 | 0.91 | EPHX1 (0.65) | EPHX1CA1CA2CES2GMNN | |
| Zinc Ion SCHEMBL966899 | 0.91 | EPHX1 (0.65) | EPHX1CA1CA2CES2GMNN | |
| Zinc Ion SCHEMBL967186 | 0.91 | EPHX1 (0.65) | EPHX1CA1CA2CES2GMNN | |
| Zinc Ion SCHEMBL965963 | 0.83 | EPHX1 (0.53) | EPHX1CA1CA2CES2CES1 | |
| SCHEMBL3715601 | 0.78 | EPHX1 (0.49) | EPHX1CA1CA2GPR84 | |
| SCHEMBL11877990 | 0.76 | EPHX1 (0.46) | EPHX1CA1CA2CES2CES1 | |
| SCHEMBL10495910 | 0.76 | EPHX1 (0.69) | EPHX1CES2GMNNTP53POLB | |
| SCHEMBL3405609 | 0.76 | EPHX1 (0.69) | EPHX1CES2GMNNTP53POLB | |
| SCHEMBL624891 | 0.76 | EPHX1 (0.69) | EPHX1CES2GMNNTP53POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 90 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0331095-B1 | Improving stability at moderate temperatures of motor vehicle components shaped from polyvinyl chloride resin compositions | WITCO CORP (US) | 1996-10-09 | — | — | EP | disclosed |
| EP-0313676-B1 | Bis-(2,2,6,6-tetramethyl-piperidyl) diimides as light stabilizers for synthetic polymers | ADEKA ARGUS CHEMICAL CO LTD (JP) | 1994-01-26 | — | — | EP | disclosed |
| US-5238979-A | Bisphenol phosphites and a phenol | ASAHI DENKA KOGYO K.K. (JP) | 1993-08-24 | — | — | US | disclosed |
| EP-0184203-B1 | VINYL BENZYL 2,2,6,6-TETRAMETHYL PIPERIDINES | ADEKA ARGUS CHEMICAL CO., Ltd. (JP) | 1992-04-15 | — | — | EP | disclosed |
| EP-0188236-B1 | POLYACETAL RESIN COMPOSITIONS HAVING IMPROVED RESISTANCE TO DETERIORATION WHEN EXPOSED TO LIGHT AND CONTAINING ALKYLIDENE BIS(BENZOTRIAZOLYL PHENOLS) | ADEKA ARGUS CHEMICAL CO., Ltd. (JP) | 1992-04-01 | — | — | EP | disclosed |
| EP-0209126-B1 | HYDROCARBYL(POLYPHENOL)-POLY(2,2,6,6-TETRAMETHYL PIPERIDYL-1,3,5-TRIAZINES) AS STABILIZERS FOR SYNTHETIC POLYMER COMPOSITIONS | ADEKA ARGUS CHEMICAL CO., Ltd. (JP) | 1992-01-02 | — | — | EP | disclosed |
| US-5055507-A | Bisphenol phosphite/phenol mixture for enhancing heat and radiation resistance | ASAHI DENKA KOGYO K.K. (JP) | 1991-10-08 | — | — | US | disclosed |
| EP-0176106-B1 | N,N',N-TRIS((2,2,6,6-TETRAMETHYL-4-PIPERIDYL)TRIAZINYL)-UNDECANE TRIAMINES AS STABILIZERS FOR SYNTHETIC POLYMERS | ADEKA ARGUS CHEMICAL CO., Ltd. (JP) | 1990-11-22 | — | — | EP | disclosed |
| EP-0395030-A1 | Polyolefin resins containing ziegler type complex catalyst residues stabilized with organic phosphites | ADEKA ARGUS CHEMICAL CO., Ltd. (JP) | 1990-10-31 | — | — | EP | disclosed |
| US-4957954-A | TETRAMETHYPIPERIDINYL COMPOUND AND PERCHLORATE | ADEKA ARGUS CHEMICAL CO., LTD. (JP) | 1990-09-18 | — | — | US | disclosed |
| EP-0069871-A2 | Copolymer light stabilizers having at least one 2,2,6,6-tetraalkyl piperidyl group and synthetic resin compositions containing the same | ADEKA ARGUS CHEMICAL CO., Ltd. (JP) | 1983-01-19 | — | — | EP | disclosed |
| EP-0068326-A2 | Bis-phenol phosphates as clarifiers for polyolefin resins | ADEKA ARGUS CHEMICAL CO., Ltd. (JP) | 1983-01-05 | — | — | EP | disclosed |
| EP-0065655-A1 | Polymeric light stabilizers having at least one 2,2,6,6-tetraalkyl piperidyl group and synthetic resin compositions containing the same | ADEKA ARGUS CHEMICAL CO., Ltd. (JP) | 1982-12-01 | — | — | EP | disclosed |
| US-4222931-A | Stabilizers for synthetic polymers comprising 2,2,6,6-tetramethyl-4-piperidyl ether alcohol or ether, phosphonic acid ester and phenolic antioxidant | ARGUS CHEMICAL CORPORATION (US) | 1980-09-16 | — | — | US | disclosed |
| US-4219463-A | Stabilizers for synthetic polymers comprising 2,2,6,6-tetramethyl-4-piperidyl carboxylic acid ester, β-thioalkyl propionic acid ester and phenol | ARGUS CHEMICAL CORPORATION (US) | 1980-08-26 | — | — | US | disclosed |
| US-4210577-A | Stabilizers for synthetic polymers comprising 2,2,6,6-tetramethyl-4-piperidyl carboxylic acid ester, phosphonic acid ester and phenol | ARGUS CHEMICAL CORPORATION (US) | 1980-07-01 | — | — | US | disclosed |
| US-4209431-A | OXIDATION AND HEAT RESISTANCE | WITCO CHEMICAL CORPORATION (US) | 1980-06-24 | — | — | US | disclosed |
| US-4080364-A | Stabilization of polyolefins against degradative deterioration as a result of exposure to light and air at elevated temperatures | ARGUS CHEMICAL CORPORATION (US) | 1978-03-21 | — | — | US | disclosed |
| US-4060513-A | BENZOPHENONE U.V. STABILIZERSPOLYOLEFIN | CINCINNATI MILACRON, INC. (US) | 1977-11-29 | — | — | US | disclosed |
| US-3997551-A | OXIDATION RESISTANCE, STABILIZE POLYMERS | ARGUS CHEMICAL CORPORATION (US) | 1976-12-14 | — | — | US | disclosed |