SCHEMBL9008360

SCHEMBL9008360

O=C(O)c1ccc(Oc2ccc3c(c2)C(=O)OC3=O)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SRD5A2 P31213 3/20 0.53
PARP15 Q460N3 1/20 0.50
PARP10 Q53GL7 1/20 0.50
MAOA P21397 1/20 0.49
MAOB P27338 1/20 0.49
AKR1C3 P42330 1/20 0.49
CA2 P00918 2/20 0.48
RXRA P19793 1/20 0.47
RXRB P28702 1/20 0.47
RXRG P48443 1/20 0.47
POLB P06746 2/20 0.46
MEN1 O00255 1/20 0.46
MAPK1 P28482 1/20 0.46
KMT2A Q03164 1/20 0.46
CA12 O43570 4/20 0.46
CA7 P43166 4/20 0.46
CA1 P00915 3/20 0.46
PDE4A P27815 1/20 0.46
PDE4B Q07343 1/20 0.46
PDE4C Q08493 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31065558 1.00 SRD5A2 (0.53) SRD5A2PARP15PARP10MAOAMAOB
SCHEMBL7822013 0.89 SRD5A2 (0.61) SRD5A2PARP15PARP10CA2POLB
SCHEMBL31634573 0.89 AKR1C3 (0.47) SRD5A2MAOAMAOBAKR1C3CA2
SCHEMBL10704760 0.89 SRD5A2 (0.50) SRD5A2PARP15PARP10MAOAMAOB
SCHEMBL10399411 0.88 AKR1C3 (0.63) PARP15PARP10MAOAMAOBAKR1C3
SCHEMBL15699449 0.87 SRD5A2 (0.41) SRD5A2PARP15PARP10MAOAMAOB
SCHEMBL30970619 0.86 MAOA (0.56) MAOAMAOBPOLB
SCHEMBL1501398 0.86 MAOA (0.56) MAOAMAOBPOLB
SCHEMBL84254 0.86 MAOA (0.56) MAOAMAOBPOLB
SCHEMBL17878211 0.86 POLB (0.48) SRD5A2PARP15PARP10MAOAMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0408473-B1 LINEAR, AROMATIC POLY(AMIDE-IMIDES) FUNCTIONALIZED THROUGH TERMINAL GROUPS CONTAINING LATENT MALEIMIDE FUNCTIONS, PROCESS FOR THEIR PREPARATION AND THEIR USE FOR PREPARING CURED POLYMERS CIBA-GEIGY AG (CH) 1993-08-11 EP claimed
US-5086154-A LINEAR AROMATIC POLY(AMIDEIMIDE)S HAVING LATENT MALEIMIDE ENDGROUPS RHONE-POULENC CHIMIE (FR) 1992-02-04 US claimed
EP-0294302-B1 IMIDE-AMIDE AND UREA-SILOXANE BLOCKS CONTAINING THERMOSTABILE BLOCKCOPOLYMERS RHONE-POULENC CHIMIE (FR) 1991-12-11 EP claimed
US-4950728-A Thermally stable (imide/amide)/(urea/siloxane) block copolymers RHONE-POULENC CHIMIE (FR) 1990-08-21 US claimed
US-4526984-A Autoxidation of alkyl-substituted aromatic ethers THE UPJOHN COMPANY (US) 1985-07-02 US claimed
WO-2018162554-A1 BIODEGRADABLE SOLVENT BASF SE (DE) 2018-09-13 WO disclosed
CN-105087019-B Liquid crystal aligning agent, liquid crystal alignment film and liquid crystal display element 奇美实业股份有限公司 2017-12-08 CN disclosed
CN-105087019-A Liquid crystal aligning agent, liquid crystal alignment film and liquid crystal display element CHI MEI CORP 2015-11-25 CN disclosed
US-20150329781-A1 LIQUID CRYSTAL ALIGNMENT AGENT, LIQUID CRYSTAL ALIGNMENT FILM, AND LIQUID CRYSTAL DISPLAY ELEMENT CHI MEI CORPORATION (TW) 2015-11-19 US disclosed
US-5576398-A POLYCARBODIIMIDES GRAFTED WITH CARBOXYLIC ANHYDRIDE AND EPOXY COMPOUND FOR MOLDING MATERIALS JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1996-11-19 US disclosed
US-5532334-A HEAT RESISTANCE KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 1996-07-02 US disclosed
US-4950728-A Thermally stable (imide/amide)/(urea/siloxane) block copolymers RHONE-POULENC CHIMIE (FR) 1990-08-21 US disclosed
US-4526984-A Autoxidation of alkyl-substituted aromatic ethers THE UPJOHN COMPANY (US) 1985-07-02 US disclosed