SCHEMBL9008367

SCHEMBL9008367

CCOC(=O)c1ccc(C(=O)O)cc1C(=O)O

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.56
HRH3 Q9Y5N1 1/20 0.52
CA12 O43570 5/20 0.51
CA1 P00915 5/20 0.51
CA2 P00918 5/20 0.51
CA7 P43166 5/20 0.51
CA9 Q16790 5/20 0.51
CA14 Q9ULX7 5/20 0.51
CYP2C9 P11712 1/20 0.50
CYP2C19 P33261 1/20 0.50
ESR1 P03372 1/20 0.49
ESR2 Q92731 1/20 0.49
LMNA P02545 2/20 0.47
CYP1A2 P05177 1/20 0.47
CYP3A4 P08684 1/20 0.47
MAOA P21397 1/20 0.47
MYC P01106 1/20 0.46
KDM4E B2RXH2 2/20 0.46
ALDH1A1 P00352 3/20 0.45
HSD17B10 Q99714 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Water SCHEMBL27703024 0.98 TSHR (0.55) TSHRHRH3CA12CA1CA2
SCHEMBL827667 0.95 TSHR (0.58) TSHRHRH3CA12CA1CA2
SCHEMBL8669772 0.93 CA12 (0.57) TSHRHRH3CA12CA1CA2
SCHEMBL6227901 0.93 HRH3 (0.52) TSHRHRH3CA12CA1CA2
SCHEMBL28542461 0.90 POLB (0.56) TSHRHRH3CA12CA1CA2
SCHEMBL2459451 0.90 TSHR (0.53) TSHRHRH3CA12CA1CA2
SCHEMBL25204328 0.90 CREBBP (0.49) TSHRHRH3CA12CA1CA2
SCHEMBL27476698 0.89 TSHR (0.51) TSHRCA12CA1CA2CA7
SCHEMBL1898128 0.89 POLB (0.54) TSHRHRH3CA12CA1CA2
SCHEMBL2292998 0.88 CA12 (0.59) TSHRHRH3CA12CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107250214-B Method for producing aromatic polyimide 罗地亚经营管理公司 2019-11-12 CN claimed
CN-107636044-A method for producing aromatic polyimide 罗地亚经营管理公司 2018-01-26 CN claimed
CN-107250214-A method for producing aromatic polyimide 罗地亚经营管理公司 2017-10-13 CN claimed
CN-107250214-B Method for producing aromatic polyimide 罗地亚经营管理公司 2019-11-12 CN disclosed
WO-2018162554-A1 BIODEGRADABLE SOLVENT BASF SE (DE) 2018-09-13 WO disclosed
CN-107636044-A method for producing aromatic polyimide 罗地亚经营管理公司 2018-01-26 CN disclosed
CN-107250214-A method for producing aromatic polyimide 罗地亚经营管理公司 2017-10-13 CN disclosed
CN-101879140-A The nanoparticle and the sustained release compositions that comprise aryl-heterocyclic compounds ELAN PHARMA INT LTD 2010-11-10 CN disclosed
CN-101287453-A Nanoparticulate and controlled release compositions comprising a cephalosporin ELAN PHARMA INT LTD (IE) 2008-10-15 CN disclosed
CN-101287451-A Nanoparticulate and controlled release compositions comprising a platelet aggregation inhibitor ELAN PHARMA INT LTD (IE) 2008-10-15 CN disclosed
CN-101242813-A Nanoparticulate and controlled release compositions comprising aryl-heterocyclic compounds ELAN PHARMA INT LTD (IE) 2008-08-13 CN disclosed
EP-0415704-B1 Catalysts for polymerization of olefins CHISSO CORP (JP) 1995-05-10 EP disclosed
US-5084429-A Coordination catalysts for olefin polymerization from magnesium, titanium, vanadium and silicon compounds CHISSO CORPORATION (JP) 1992-01-28 US disclosed
EP-0415704-A2 Catalysts for polymerization of olefins CHISSO CORPORATION (JP) 1991-03-06 EP disclosed
EP-0248932-B1 PROCESS FOR PREPARING POLYAMIDES Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1991-01-09 EP disclosed
US-4754016-A Process for preparing polyamide with organic phosphine/organic disulfide mixture condensing agent ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1988-06-28 US disclosed
EP-0248932-A1 Process for preparing polyamides Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1987-12-16 EP disclosed
EP-0017422-B1 THERMOPLASTIC POLYAMIDEIMIDE COPOLYMERS AND METHOD OF PREPARATION TORAY INDUSTRIES, INC. (JP) 1983-11-30 EP disclosed
US-4299945-A HEAT POLYMERIZATION OF AN AROMATIC DIAMINO COMPOUND AND AN AROMATIC TRIBASIC CARBOXYLIC ACID TORAY INDUSTRIES, INC. (JP) 1981-11-10 US disclosed
EP-0017422-A1 Thermoplastic polyamideimide copolymers and method of preparation TORAY INDUSTRIES, INC. (JP) 1980-10-15 EP disclosed