SCHEMBL8669772

SCHEMBL8669772

CCOC(=O)c1ccc(C(=O)OCC)c(C(=O)O)c1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 5/20 0.57
CA1 P00915 5/20 0.57
CA2 P00918 5/20 0.57
CA7 P43166 5/20 0.57
CA9 Q16790 5/20 0.57
CA14 Q9ULX7 5/20 0.57
TSHR P16473 2/20 0.56
ESR1 P03372 1/20 0.53
ESR2 Q92731 1/20 0.53
LMNA P02545 1/20 0.51
CYP1A2 P05177 1/20 0.51
CYP3A4 P08684 1/20 0.51
MAOA P21397 1/20 0.51
HSD17B2 P37059 1/20 0.51
ALDH1A1 P00352 2/20 0.50
MAPK1 P28482 1/20 0.50
CYP2C9 P11712 1/20 0.50
CYP2C19 P33261 1/20 0.50
HCRTR1 O43613 2/20 0.48
MEN1 O00255 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2292998 0.95 CA12 (0.59) CA12CA1CA2CA7CA9
SCHEMBL9008367 0.93 TSHR (0.56) CA12CA1CA2CA7CA9
SCHEMBL27562005 0.92 CA12 (0.53) CA12CA1CA2CA7CA9
SCHEMBL27476698 0.92 TSHR (0.51) CA12CA1CA2CA7CA9
SCHEMBL31070226 0.92 CA12 (0.53) CA12CA1CA2CA7CA9
Water SCHEMBL27703024 0.92 TSHR (0.55) CA12CA1CA2CA7CA9
SCHEMBL321387 0.91 CA12 (0.62) CA12CA1CA2CA7CA9
SCHEMBL29843135 0.91 CA12 (0.62) CA12CA1CA2CA7CA9
SCHEMBL28542461 0.90 POLB (0.56) CA12CA1CA2CA7CA9
SCHEMBL1898128 0.89 POLB (0.54) CA12CA1CA2CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1962599-B Method for hydrogenating benzene polycarboxylic acids or derivatives thereof by using catalyst containing macropores BASF AG 2014-05-14 CN disclosed
CN-100406428-C Process for hydrogenating benzenepolycarboxylic acids or derivatives thereof using catalysts containing macropores BASF AG (DE) 2008-07-30 CN disclosed
CN-1962599-A Method for hydrogenating benzene polycarboxylic acids or derivatives thereof by using a catalyst containing macropores BASF AG (DE) 2007-05-16 CN disclosed
CN-1241882-C Method for hydrogenating organic compounds by means of RU/SIO2 catalysts BASF AG (DE) 2006-02-15 CN disclosed
CN-1285815-A Process for hydrogenating benzenepolycarboxylic acids or derivatives thereof using catalysts containing macropores BASF AG (DE) 2001-02-28 CN disclosed
EP-0642569-B1 POLYESTERS OF POLY(OXYALKYLENE) HYDROXYAROMATIC ETHERS CHEVRON CHEM CO (US) 1998-12-16 EP disclosed
EP-0642569-A4 POLYESTERS OF POLY(OXYALKYLENE) HYDROXYAROMATIC ETHERS. CHEVRON CHEM CO (US) 1995-08-09 EP disclosed
EP-0642569-A1 POLYESTERS OF POLY(OXYALKYLENE) HYDROXYAROMATIC ETHERS CHEVRON CHEMICAL COMPANY (US) 1995-03-15 EP disclosed
WO-1994020592-A1 POLYESTERS OF POLY(OXYALKYLENE) HYDROXYAROMATIC ETHERS CHEVRON RESEARCH AND TECHNOLOGY COMPANY A DIVISION OF CHEVRON U.S.A. INC. (US) 1994-09-15 WO disclosed
US-5296003-A Fuel additives CHEVRON RESEARCH AND TECHNOLOGY COMPANY (US) 1994-03-22 US disclosed