Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 11/20 | 0.39 |
| ▸ | TLR7 | Q9NYK1 | 6/20 | 0.37 |
| ▸ | HTR7 | P34969 | 7/20 | 0.36 |
| ▸ | HTR1A | P08908 | 6/20 | 0.36 |
| ▸ | DRD2 | P14416 | 6/20 | 0.36 |
| ▸ | HTR2A | P28223 | 6/20 | 0.36 |
| ▸ | HTR6 | P50406 | 6/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | CDK9 | P50750 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9008414 | 0.97 | HTR7 (0.39) | TLR8TLR7HTR7KDM4EMEN1 | |
| SCHEMBL9008390 | 0.88 | SLC29A1 (0.38) | LMNAMAPTHTTKMT2ATSHR | |
| SCHEMBL9008409 | 0.82 | SLC29A1 (0.39) | TLR8TLR7KDM4EMEN1NPC1 | |
| SCHEMBL9008416 | 0.81 | SLC29A1 (0.50) | MEN1NPC1ALDH1A1LMNAMAPT | |
| SCHEMBL28364685 | 0.80 | HTR7 (0.43) | TLR8TLR7HTR7HTR1ADRD2 | |
| SCHEMBL28364574 | 0.77 | HRH3 (0.44) | TLR8TLR7HTR7HTR1ADRD2 | |
| SCHEMBL554834 | 0.75 | TLR8 (0.55) | TLR8TLR7KDM4EMEN1NPC1 | |
| SCHEMBL28589569 | 0.75 | TLR8 (0.55) | TLR8TLR7KDM4EMEN1NPC1 | |
| SCHEMBL1411113 | 0.74 | HTR7 (0.46) | TLR8TLR7HTR7HTR1ADRD2 | |
| SCHEMBL1411032 | 0.74 | HTR7 (0.50) | TLR8TLR7HTR7HTR1ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-8325247-A | — | — | None | — | — | JP | disclosed |
| JP-H08325247-A | FORMALDEHYDE-FREE CROSSLINKING AGENT FOR COATING BINDER | HOECHST AG | 1996-12-10 | — | — | JP | disclosed |
| EP-0738719-A1 | Formaldehyde-free crosslinkers for lacquer binding agents | Vianova Resins GmbH (DE) | 1996-10-23 | — | — | EP | disclosed |