Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3A | P49840 | 2/20 | 0.40 |
| ▸ | GSK3B | P49841 | 2/20 | 0.40 |
| ▸ | KAT2B | Q92831 | 4/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | MPI | P34949 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27296782 | 0.78 | GSK3A (0.40) | GSK3AGSK3BMPIKMT2AMEN1 | |
| SCHEMBL676935 | 0.68 | GSK3A (0.41) | GSK3AGSK3BKAT2BMPIKMT2A | |
| SCHEMBL11030142 | 0.68 | GSK3A (0.41) | GSK3AGSK3BKAT2BMPIKMT2A | |
| SCHEMBL9743310 | 0.68 | KAT2B (0.37) | KAT2BCA12CA1CA9 | |
| SCHEMBL9576566 | 0.67 | GSK3A (0.37) | GSK3AGSK3BMPIKMT2AMEN1 | |
| SCHEMBL80964 | 0.65 | GSK3A (0.39) | GSK3AGSK3BKAT2BMPIKMT2A | |
| SCHEMBL9350668 | 0.63 | ALDH1A1 (0.44) | GSK3AGSK3BKMT2AMEN1NPSR1 | |
| SCHEMBL8346184 | 0.63 | MPI (0.36) | GSK3AGSK3BKAT2BMPIKMT2A | |
| SCHEMBL29239065 | 0.62 | GSK3A (0.65) | GSK3AGSK3BMPIKMT2AMEN1 | |
| SCHEMBL3472019 | 0.61 | ALDH1A1 (0.60) | KMT2AMEN1ALDH1A1SMN1; SMN2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1034807-C | Bromate as inhibitor of nitrosamine formation for nitrate stabilized isothiazolones and process | ROHM & HAAS (US) | 1997-05-07 | — | — | CN | claimed |
| EP-0540213-B1 | Bromate as an inhibitor of nitrosamine formation in nitrate stabilized isothiazolones | ROHM & HAAS (US) | 1996-10-30 | — | — | EP | claimed |
| EP-0542408-B1 | Bromate stabilizers for 3-isothiazolones | ROHM & HAAS (US) | 1996-01-10 | — | — | EP | claimed |
| EP-0542408-A1 | Bromate stabilizers for 3-isothiazolones | ROHM AND HAAS COMPANY (US) | 1993-05-19 | — | — | EP | claimed |
| CN-1071921-A | Be used for suppressing to be formed the bromate and the method for nitrosamine by nitrate stabilized isothiazolones | ROHM & HAAS (US) | 1993-05-12 | — | — | CN | claimed |
| EP-0540213-A1 | Bromate as an inhibitor of nitrosamine formation in nitrate stabilized isothiazolones | ROHM AND HAAS COMPANY (US) | 1993-05-05 | — | — | EP | claimed |
| US-5145501-A | Fungicides, algicides, bactericides | ROHM AND HAAS COMPANY (US) | 1992-09-08 | — | — | US | claimed |
| US-5137899-A | Amidation of disulfide ester, halogenation-cyclization, nuetralization, stabilization and heat treatment | ROHM AND HAAS COMPANY (US) | 1992-08-11 | — | — | US | claimed |
| CN-1034807-C | Bromate as inhibitor of nitrosamine formation for nitrate stabilized isothiazolones and process | ROHM & HAAS (US) | 1997-05-07 | — | — | CN | disclosed |
| EP-0540213-B1 | Bromate as an inhibitor of nitrosamine formation in nitrate stabilized isothiazolones | ROHM & HAAS (US) | 1996-10-30 | — | — | EP | disclosed |
| EP-0542408-B1 | Bromate stabilizers for 3-isothiazolones | ROHM & HAAS (US) | 1996-01-10 | — | — | EP | disclosed |
| EP-0542408-A1 | Bromate stabilizers for 3-isothiazolones | ROHM AND HAAS COMPANY (US) | 1993-05-19 | — | — | EP | disclosed |
| CN-1071921-A | Be used for suppressing to be formed the bromate and the method for nitrosamine by nitrate stabilized isothiazolones | ROHM & HAAS (US) | 1993-05-12 | — | — | CN | disclosed |
| EP-0540213-A1 | Bromate as an inhibitor of nitrosamine formation in nitrate stabilized isothiazolones | ROHM AND HAAS COMPANY (US) | 1993-05-05 | — | — | EP | disclosed |
| US-5145501-A | Fungicides, algicides, bactericides | ROHM AND HAAS COMPANY (US) | 1992-09-08 | — | — | US | disclosed |
| US-5137899-A | Amidation of disulfide ester, halogenation-cyclization, nuetralization, stabilization and heat treatment | ROHM AND HAAS COMPANY (US) | 1992-08-11 | — | — | US | disclosed |