Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.74 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.74 |
| ▸ | ADRB2 | P07550 | 5/20 | 0.71 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.71 |
| ▸ | ADRB1 | P08588 | 4/20 | 0.71 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.71 |
| ▸ | MAPT | P10636 | 1/20 | 0.70 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.63 |
| ▸ | MEN1 | O00255 | 1/20 | 0.63 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.63 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.63 |
| ▸ | TSHR | P16473 | 1/20 | 0.63 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.63 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.63 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.63 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.63 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL611850 | 0.88 | PTGS1 (0.70) | PTGS1SLC6A2ADRB2CYP2D6ADRB1 | |
| Prenalterol SCHEMBL10816429 | 0.85 | PTGS1 (1.00) | PTGS1SLC6A2ADRB2CYP2D6ADRB1 | |
| Prenalterol SCHEMBL249753 | 0.85 | PTGS1 (1.00) | PTGS1SLC6A2ADRB2CYP2D6ADRB1 | |
| SCHEMBL7946116 | 0.85 | PTGS1 (0.77) | PTGS1SLC6A2ADRB2CYP2D6ADRB1 | |
| Prenalterol SCHEMBL10788435 | 0.85 | PTGS1 (1.00) | PTGS1SLC6A2ADRB2CYP2D6ADRB1 | |
| SCHEMBL22639751 | 0.85 | PTGS1 (0.77) | PTGS1SLC6A2ADRB2CYP2D6ADRB1 | |
| SCHEMBL10913734 | 0.84 | PTGS1 (0.70) | PTGS1SLC6A2ADRB2CYP2D6ADRB1 | |
| SCHEMBL7953135 | 0.84 | PTGS1 (0.74) | PTGS1SLC6A2ADRB2CYP2D6ADRB1 | |
| Prenalterol SCHEMBL121857 | 0.84 | PTGS1 (0.97) | PTGS1SLC6A2ADRB2CYP2D6ADRB1 | |
| SCHEMBL5390387 | 0.84 | PTGS1 (0.74) | PTGS1SLC6A2ADRB2CYP2D6ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0552379-B1 | DIHYDROPYRIDINE DERIVATIVES, AND PROCESS FOR THEIR PREPARATION | FUJISAWA PHARMACEUTICAL CO (JP) | 1996-10-30 | — | — | EP | disclosed |
| EP-0228192-A2 | Renin-inhibitory oligopeptides, their preparation and use | SANKYO COMPANY LIMITED (JP) | 1987-07-08 | — | — | EP | disclosed |