Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 2/20 | 0.42 |
| ▸ | P2RY14 | Q15391 | 7/20 | 0.39 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.38 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ADRB3 | P13945 | 3/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.35 |
| ▸ | DRD1 | P21728 | 3/20 | 0.35 |
| ▸ | DRD5 | P21918 | 3/20 | 0.35 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.35 |
| ▸ | TMEM97 | Q5BJF2 | 3/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7759567 | 1.00 | HTR2C (0.42) | HTR2CP2RY14DGAT1SOAT1ALDH1A1 | |
| SCHEMBL8019251 | 1.00 | HTR2C (0.42) | HTR2CP2RY14DGAT1SOAT1ALDH1A1 | |
| SCHEMBL7759570 | 1.00 | HTR2C (0.42) | HTR2CP2RY14DGAT1SOAT1ALDH1A1 | |
| SCHEMBL8016818 | 0.88 | CYP2C9 (0.38) | DGAT1ALDH1A1LMNAMAPTCYP2C9 | |
| SCHEMBL7759591 | 0.88 | CYP2C9 (0.38) | DGAT1ALDH1A1LMNAMAPTCYP2C9 | |
| SCHEMBL9008545 | 0.88 | CYP2C9 (0.38) | DGAT1ALDH1A1LMNAMAPTCYP2C9 | |
| SCHEMBL7759580 | 0.88 | CYP2C9 (0.38) | DGAT1ALDH1A1LMNAMAPTCYP2C9 | |
| SCHEMBL8014726 | 0.88 | P2RY14 (0.33) | HTR2CP2RY14DGAT1SOAT1ALDH1A1 | |
| SCHEMBL8014720 | 0.88 | P2RY14 (0.33) | HTR2CP2RY14DGAT1SOAT1ALDH1A1 | |
| SCHEMBL8014715 | 0.88 | P2RY14 (0.33) | HTR2CP2RY14DGAT1SOAT1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5582764-A | Silacyclohexane compound, a method of preparing it and a liquid crystal composition containing it | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1996-12-10 | — | — | US | disclosed |