Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 3/20 | 0.53 |
| ▸ | ELANE | P08246 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | PIM1 | P11309 | 1/20 | 0.44 |
| ▸ | BACE1 | P56817 | 1/20 | 0.44 |
| ▸ | GAPDH | P04406 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9008559 | 0.91 | MAPT (0.53) | TTRELANEKDM4EMAPTSMN1; SMN2 | |
| SCHEMBL11213111 | 0.86 | MAPT (0.55) | TTRELANEKDM4EMAPTSMN1; SMN2 | |
| SCHEMBL22336250 | 0.83 | MAPT (0.55) | TTRELANEKDM4EMAPTSMN1; SMN2 | |
| SCHEMBL15085173 | 0.81 | MAPT (0.62) | TTRELANEKDM4EMAPTSMN1; SMN2 | |
| SCHEMBL497339 | 0.81 | MAPT (0.60) | TTRKDM4EMAPTSMN1; SMN2KMT2A | |
| SCHEMBL29551111 | 0.81 | MAPT (0.60) | TTRKDM4EMAPTSMN1; SMN2KMT2A | |
| SCHEMBL4642778 | 0.80 | MAPT (0.61) | TTRELANEMAPTSMN1; SMN2KMT2A | |
| SCHEMBL9008506 | 0.78 | TTR (0.51) | TTRKDM4EMAPTSMN1; SMN2KMT2A | |
| SCHEMBL14627948 | 0.78 | BACE1 (0.59) | TTRELANEKDM4EMAPTSMN1; SMN2 | |
| SCHEMBL7173911 | 0.77 | ELANE (0.75) | TTRELANEKDM4EMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5484935-A | Pharmaceutical compounds | LILLY INDUSTRIES LIMITED (GB) | 1996-01-16 | — | — | US | claimed |
| EP-0638562-A1 | Anthraquinone derivatives useful in the treatment of cancer and osteoartritis | LILLY INDUSTRIES LIMITED (GB) | 1995-02-15 | — | — | EP | claimed |
| US-5484935-A | Pharmaceutical compounds | LILLY INDUSTRIES LIMITED (GB) | 1996-01-16 | — | — | US | disclosed |
| EP-0638562-A1 | Anthraquinone derivatives useful in the treatment of cancer and osteoartritis | LILLY INDUSTRIES LIMITED (GB) | 1995-02-15 | — | — | EP | disclosed |