SCHEMBL497339

SCHEMBL497339

CC(=O)Oc1ccc(OC(C)=O)c2c1C(=O)c1ccccc1C2=O

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 7/20 0.60
MEN1 O00255 5/20 0.60
ALDH1A1 P00352 5/20 0.60
KMT2A Q03164 5/20 0.60
KDM4E B2RXH2 5/20 0.60
TDP1 Q9NUW8 3/20 0.60
USP2 O75604 2/20 0.60
DUSP3 P51452 1/20 0.60
TTR P02766 2/20 0.56
SMN1; SMN2 Q16637 4/20 0.50
RAB9A P51151 4/20 0.50
LMNA P02545 4/20 0.50
HPGD P15428 3/20 0.50
MAPK1 P28482 2/20 0.50
ADORA2A P29274 2/20 0.50
TP53 P04637 2/20 0.50
POLB P06746 2/20 0.50
HTT P42858 2/20 0.50
PIM1 P11309 1/20 0.50
ABCC4 O15439 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29551111 1.00 MAPT (0.60) MAPTMEN1ALDH1A1KMT2AKDM4E
SCHEMBL13183079 0.92 MAPT (0.61) MAPTMEN1ALDH1A1KMT2AKDM4E
SCHEMBL11101186 0.87 TTR (0.72) MAPTMEN1ALDH1A1KMT2AKDM4E
SCHEMBL4645309 0.83 SMN1; SMN2 (0.58) MAPTMEN1ALDH1A1KMT2AKDM4E
SCHEMBL3959473 0.83 MAPT (0.69) MAPTMEN1ALDH1A1KMT2AKDM4E
SCHEMBL5306728 0.82 MAPT (0.57) MAPTMEN1ALDH1A1KMT2AKDM4E
SCHEMBL11526060 0.82 EGFR (0.63) MAPTMEN1ALDH1A1KMT2AKDM4E
SCHEMBL11107245 0.82 TTR (0.54) MAPTMEN1ALDH1A1KMT2AKDM4E
SCHEMBL9008510 0.81 TTR (0.53) MAPTMEN1ALDH1A1KMT2AKDM4E
SCHEMBL22343407 0.81 HTT (0.57) MAPTMEN1ALDH1A1KMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8105477-B2 System and method for electrochemical detection of biological compounds HANDYLAB, INC. (US) 2012-01-31 US disclosed
US-20110039345-A1 SYSTEM AND METHOD FOR ELECTROCHEMICAL DETECTION OF BIOLOGICAL COMPOUNDS HANDYLAB, INC. (US) 2011-02-17 US disclosed
US-7820030-B2 System and method for electrochemical detection of biological compounds HANDYLAB, INC. (US) 2010-10-26 US disclosed
US-20060207891-A1 System and method for electrochemical detection of biological compounds HANDYLAB, INC. (US) 2006-09-21 US disclosed
WO-2004094986-A2 SYSTEM AND METHOD FOR ELECTROCHEMICAL DETECTION OF BIOLOGICAL COMPOUNDS HANDYLAB, INC. (US) 2004-11-04 WO disclosed