Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 9/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 8/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 8/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8021295 | 1.00 | KIF11 (0.33) | KIF11CYP11B1CYP11B2KDM1AHTR2A | |
| SCHEMBL8021287 | 1.00 | KIF11 (0.33) | KIF11CYP11B1CYP11B2KDM1AHTR2A | |
| SCHEMBL8021291 | 1.00 | KIF11 (0.33) | KIF11CYP11B1CYP11B2KDM1AHTR2A | |
| SCHEMBL8014726 | 0.88 | P2RY14 (0.33) | HTR2C | |
| SCHEMBL8014715 | 0.88 | P2RY14 (0.33) | HTR2C | |
| SCHEMBL8014720 | 0.88 | P2RY14 (0.33) | HTR2C | |
| SCHEMBL9008543 | 0.88 | P2RY14 (0.33) | HTR2C | |
| SCHEMBL7762536 | 0.88 | KDM1A (0.37) | KDM1AHTR2A | |
| SCHEMBL7762527 | 0.88 | KDM1A (0.37) | KDM1AHTR2A | |
| SCHEMBL7762532 | 0.88 | KDM1A (0.37) | KDM1AHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5582764-A | Silacyclohexane compound, a method of preparing it and a liquid crystal composition containing it | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1996-12-10 | — | — | US | disclosed |