Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB1 | P46663 | 6/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CCKBR | P32239 | 6/20 | 0.36 |
| ▸ | CCKAR | P32238 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | OXTR | P30559 | 1/20 | 0.34 |
| ▸ | CSF1R | P07333 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9008683 | 0.87 | CCKBR (0.45) | BDKRB1CCKBRCCKAR | |
| SCHEMBL9008792 | 0.87 | CCKBR (0.45) | BDKRB1CCKBRCCKAR | |
| SCHEMBL9008684 | 0.81 | BDKRB1 (0.45) | BDKRB1CCKBRCCKAROXTR | |
| SCHEMBL7592838 | 0.81 | BDKRB1 (0.55) | BDKRB1CCKBRCCKAR | |
| SCHEMBL9008659 | 0.79 | CCKBR (0.41) | BDKRB1KDM4ECCKBROXTR | |
| SCHEMBL9008744 | 0.79 | CCKBR (0.42) | BDKRB1CCKBRCCKAROXTR | |
| SCHEMBL9008853 | 0.78 | BDKRB1 (0.59) | BDKRB1CCKBR | |
| SCHEMBL9008785 | 0.78 | EPHX2 (0.41) | KDM4ECCKBR | |
| SCHEMBL9008842 | 0.76 | MAPT (0.43) | BDKRB1KDM4EMAPTCCKBRCCKAR | |
| SCHEMBL9008676 | 0.76 | MAPT (0.43) | BDKRB1KDM4EMAPTCCKBRCCKAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5556969-A | Benzodiazepine derivatives | MERCK SHARP & DOHME LTD. (GB) | 1996-09-17 | — | — | US | claimed |