Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 17/20 | 0.67 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.57 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9008677 | 1.00 | CCKBR (0.67) | CCKBREPHX2BDKRB1 | |
| SCHEMBL9008675 | 0.87 | CCKBR (0.70) | CCKBRBDKRB1 | |
| SCHEMBL9008860 | 0.87 | CCKBR (0.70) | CCKBRBDKRB1 | |
| SCHEMBL9008724 | 0.83 | CCKBR (0.65) | CCKBRBDKRB1 | |
| SCHEMBL9008885 | 0.82 | CCKBR (0.73) | CCKBRBDKRB1 | |
| SCHEMBL9008663 | 0.82 | CCKBR (0.73) | CCKBRBDKRB1 | |
| SCHEMBL14180441 | 0.81 | CCKBR (0.84) | CCKBRBDKRB1 | |
| SCHEMBL14425311 | 0.81 | CCKBR (1.00) | CCKBR | |
| SCHEMBL9301528 | 0.81 | CCKBR (1.00) | CCKBR | |
| SCHEMBL14180463 | 0.80 | CCKBR (0.82) | CCKBR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5556969-A | Benzodiazepine derivatives | MERCK SHARP & DOHME LTD. (GB) | 1996-09-17 | — | — | US | disclosed |