Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | KCNN4 | O15554 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.35 |
| ▸ | DRD1 | P21728 | 1/20 | 0.35 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | OXTR | P30559 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18257237 | 0.87 | DRD1 (0.39) | KMT2AKCNN4HTTSMN1; SMN2P2RX7 | |
| SCHEMBL13263183 | 0.83 | KCNN4 (0.41) | KMT2AKCNN4POLBKCNH2ACHE | |
| SCHEMBL16955002 | 0.81 | MAPT (0.46) | KMT2APOLBSLC6A2SLC6A4DRD1 | |
| SCHEMBL27451265 | 0.79 | CA12 (0.42) | KCNN4SMN1; SMN2P2RX7NR1I2GAA | |
| Hydrochloric Acid SCHEMBL1290809 | 0.79 | ALDH1A1 (0.38) | SLC6A2SLC6A4HTTACHESLC6A3 | |
| SCHEMBL23588427 | 0.78 | SLC6A2 (0.48) | KMT2AKCNN4POLBSLC6A2SLC6A4 | |
| SCHEMBL7782409 | 0.78 | KMT2A (0.53) | KMT2AKCNN4POLBSLC6A2SLC6A4 | |
| SCHEMBL22333018 | 0.78 | ALDH1A1 (0.37) | KMT2AHTTSMN1; SMN2P2RX7DRD1 | |
| SCHEMBL16955000 | 0.78 | DRD1 (0.34) | KMT2AKCNN4HTTSMN1; SMN2P2RX7 | |
| SCHEMBL900625 | 0.78 | ALDH1A1 (0.45) | KMT2APOLBHTTP2RX7ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023078411-A1 | AZASPIRO COMPOUND | 南京明德新药研发有限公司 | 2023-05-11 | — | — | WO | disclosed |
| EP-2621922-A1 | A PROCESS FOR THE SYNTHESIS OF THIO-TRIAZOLO-GROUP CONTAINING COMPOUNDS | BASF SE (DE) | 2013-08-07 | — | — | EP | disclosed |
| WO-2012041858-A1 | A PROCESS FOR THE SYNTHESIS OF THIO-TRIAZOLO-GROUP CONTAINING COMPOUNDS | BASF SE (DE) | 2012-04-05 | — | — | WO | disclosed |