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SCHEMBL9009253

SCHEMBL9009253

CNC(C(=O)Nc1c(I)c(C(=O)NCC(O)CO)c(I)c(C(=O)NCC(O)CO)c1I)C(=O)c1c(I)c(NC(=O)COC)c(I)c(C(=O)NCC(O)CO)c1I

nearest known ligand 0.65

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ LMNA P02545 3/20 0.65
▸ CYP2C19 P33261 1/20 0.42
▸ HIF1A Q16665 1/20 0.42
▸ SMN1; SMN2 Q16637 1/20 0.31
▸ EGFR P00533 1/20 0.30
▸ SRC P12931 1/20 0.30
▸ HPGD P15428 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9009050 0.92 LMNA (0.56) LMNACYP2C19HIF1ASMN1; SMN2
SCHEMBL12885813 0.88 LMNA (0.80) LMNACYP2C19HIF1ASMN1; SMN2EGFR
SCHEMBL9009295 0.88 LMNA (0.60) LMNACYP2C19HIF1A
SCHEMBL9009243 0.87 LMNA (0.64) LMNACYP2C19HIF1A
SCHEMBL28634498 0.86 LMNA (0.74) LMNACYP2C19HIF1ASMN1; SMN2EGFR
SCHEMBL9192161 0.85 LMNA (0.75) LMNACYP2C19HIF1ASMN1; SMN2EGFR
SCHEMBL29557408 0.84 LMNA (0.74) LMNACYP2C19HIF1ASMN1; SMN2EGFR
SCHEMBL8857302 0.84 LMNA (0.74) LMNACYP2C19HIF1ASMN1; SMN2EGFR
SCHEMBL30480271 0.83 LMNA (0.72) LMNACYP2C19HIF1ASMN1; SMN2EGFR
SCHEMBL12217873 0.83 LMNA (0.72) LMNACYP2C19HIF1ASMN1; SMN2EGFR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0571593-B1 NEW NON IONIC IODIZED AGENTS FOR X-RAY CONTRASTING, METHOD FOR PREPARING THEM AND GALENICAL COMPOSITIONS CONTAINING THEM INVEST JUSTESA IMAGEN S A CENT (ES) 1996-10-30 — — EP disclosed