Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | MAP2K1 | Q02750 | 5/20 | 0.31 |
| ▸ | MAP2K2 | P36507 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.31 |
| ▸ | IARS2 | Q9NSE4 | 1/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.30 |
| ▸ | SRC | P12931 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9009059 | 0.91 | LMNA (0.48) | LMNACYP2C19HIF1ASMN1; SMN2 | |
| SCHEMBL9009257 | 0.86 | LMNA (0.63) | LMNACYP2C19HIF1ASMN1; SMN2 | |
| SCHEMBL9009330 | 0.86 | LMNA (0.63) | LMNACYP2C19HIF1ASMN1; SMN2 | |
| SCHEMBL9352694 | 0.83 | LMNA (0.47) | LMNACYP2C19HIF1ASMN1; SMN2 | |
| SCHEMBL9009193 | 0.80 | LMNA (0.55) | LMNACYP2C19HIF1AMAP2K1MAP2K2 | |
| SCHEMBL9009162 | 0.79 | LMNA (0.48) | LMNACYP2C19HIF1ASMN1; SMN2 | |
| SCHEMBL9009240 | 0.79 | LMNA (0.53) | LMNACYP2C19HIF1ASMN1; SMN2 | |
| SCHEMBL9009297 | 0.79 | LMNA (0.40) | LMNACYP2C19HIF1AMAP2K1MAP2K2 | |
| SCHEMBL9284452 | 0.79 | LMNA (0.38) | LMNACYP2C19HIF1ATSHRMAPK1 | |
| SCHEMBL9009065 | 0.78 | LMNA (0.50) | LMNACYP2C19HIF1ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0571593-B1 | NEW NON IONIC IODIZED AGENTS FOR X-RAY CONTRASTING, METHOD FOR PREPARING THEM AND GALENICAL COMPOSITIONS CONTAINING THEM | INVEST JUSTESA IMAGEN S A CENT (ES) | 1996-10-30 | — | — | EP | claimed |