SCHEMBL9009342

SCHEMBL9009342

COCC(=O)Nc1c(I)c(C(=O)NC(I)C(=O)Nc2c(I)c(C(=O)NC(CO)C(O)CO)c(I)c(C(=O)NC(CO)C(O)CO)c2I)cc(C(=O)NC(CO)C(O)CO)c1I

nearest known ligand 0.43

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.43
SMN1; SMN2 Q16637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9009272 0.93 LMNA (0.52) LMNA
SCHEMBL9009340 0.92 LMNA (0.55) LMNA
SCHEMBL9009299 0.89 LMNA (0.59) LMNA
SCHEMBL9009284 0.83 LMNA (0.40) LMNA
SCHEMBL9009355 0.81 LMNA (0.51) LMNA
SCHEMBL9009240 0.80 LMNA (0.53) LMNASMN1; SMN2
SCHEMBL9009297 0.78 LMNA (0.40) LMNASMN1; SMN2
SCHEMBL9009223 0.78 LMNA (0.56) LMNA
SCHEMBL9009197 0.77 LMNA (0.72) LMNA
SCHEMBL9009330 0.76 LMNA (0.63) LMNASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0571593-B1 NEW NON IONIC IODIZED AGENTS FOR X-RAY CONTRASTING, METHOD FOR PREPARING THEM AND GALENICAL COMPOSITIONS CONTAINING THEM INVEST JUSTESA IMAGEN S A CENT (ES) 1996-10-30 EP claimed