⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL90401 | 0.92 | — | — | |
| SCHEMBL90164 | 0.74 | — | — | |
| SCHEMBL1753465 | 0.69 | SOS1 (0.32) | — | |
| SCHEMBL7131245 | 0.69 | — | — | |
| SCHEMBL30065459 | 0.67 | — | — | |
| SCHEMBL90801 | 0.67 | — | — | |
| SCHEMBL14962053 | 0.67 | SOS1 (0.52) | — | |
| SCHEMBL14962054 | 0.67 | — | — | |
| SCHEMBL766013 | 0.67 | — | — | |
| SCHEMBL12314024 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11548888-B2 | KRas G12C inhibitors | Mirati Therapeutics, Inc. (US) | 2023-01-10 | — | — | US | disclosed |
| EP-3303326-B1 | HETEROCYCLIC ESTROGEN RECEPTOR MODULATORS AND USES THEREOF | HOFFMANN LA ROCHE (CH) | 2020-12-16 | — | — | EP | disclosed |
| US-20160347742-A1 | HETEROCYCLIC ESTROGEN RECEPTOR MODULATORS AND USES THEREOF | GENENTECH, INC. (US) | 2016-12-01 | — | — | US | disclosed |
| WO-2016189011-A1 | HETEROCYCLIC ESTROGEN RECEPTOR MODULATORS AND USES THEREOF | F. HOFFMANN-LA ROCHE AG (CH) | 2016-12-01 | — | — | WO | disclosed |
| EP-2154141-B1 | Precursors for depositing silicon-containing films and methods using same | AIR PROD & CHEM (US) | 2016-06-15 | — | — | EP | disclosed |
| US-9302988-B2 | Fluoromethyl-substituted pyrrole carboxamides | Grünenthal GmbH (DE) | 2016-04-05 | — | — | US | disclosed |
| EP-2644609-B1 | Precursors for depositing silicon-containing films and methods of using same | AIR PROD & CHEM (US) | 2015-07-08 | — | — | EP | disclosed |
| US-20140066426-A1 | FLUOROMETHYL-SUBSTITUTED PYRROLE CARBOXAMIDES | GRUENENTHAL GMBH (DE) | 2014-03-06 | — | — | US | disclosed |
| EP-2644609-A2 | Precursors for depositing silicon-containing films and methods for making and using same | AIR PRODUCTS AND CHEMICALS, INC. (US) | 2013-10-02 | — | — | EP | disclosed |
| US-8129555-B2 | Precursors for depositing silicon-containing films and methods for making and using same | AIR PRODUCTS AND CHEMICALS, INC. (US) | 2012-03-06 | — | — | US | disclosed |
| US-8129555-B2 | Precursors for depositing silicon-containing films and methods for making and using same | AIR PRODUCTS AND CHEMICALS, INC. (US) | 2012-03-06 | — | — | US | disclosed |
| US-20100041243-A1 | Precursors for Depositing Silicon-containing Films and Methods for Making and Using Same | AIR PRODUCTS AND CHEMICALS, INC. (US) | 2010-02-18 | — | — | US | disclosed |
| US-20100041243-A1 | Precursors for Depositing Silicon-containing Films and Methods for Making and Using Same | AIR PRODUCTS AND CHEMICALS, INC. (US) | 2010-02-18 | — | — | US | disclosed |