Biphenyl

Biphenyl

SCHEMBL9009477

O=[PH](O)O.O=[PH](O)O.c1ccc(-c2ccccc2)cc1

nearest known ligand 0.60

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.60
MMP3 P08254 1/20 0.50
BCL2L1 Q07817 1/20 0.50
MAPT P10636 2/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
WDR5 P61964 1/20 0.46
LMNA P02545 2/20 0.44
HTT P42858 2/20 0.44
ABCC4 O15439 1/20 0.44
GAA P10253 1/20 0.44
TSHR P16473 1/20 0.44
PTGS1 P23219 1/20 0.44
CA1 P00915 1/20 0.43
CA2 P00918 1/20 0.43
MGLL Q99685 1/20 0.43
RAB9A P51151 2/20 0.43
MAPK1 P28482 1/20 0.43
MEN1 O00255 1/20 0.43
POLB P06746 1/20 0.43
KMT2A Q03164 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Biphenyl SCHEMBL987489 1.00 ALDH1A1 (0.60) ALDH1A1MMP3BCL2L1MAPTSMN1; SMN2
Biphenyl SCHEMBL11137586 1.00 ALDH1A1 (0.60) ALDH1A1MMP3BCL2L1MAPTSMN1; SMN2
Biphenyl SCHEMBL5916273 0.97 ALDH1A1 (0.56) ALDH1A1MMP3BCL2L1MAPTSMN1; SMN2
Biphenyl SCHEMBL28773738 0.91 ALDH1A1 (0.50) ALDH1A1MMP3BCL2L1MAPTSMN1; SMN2
Biphenyl SCHEMBL22574598 0.88 ALDH1A1 (0.53) ALDH1A1MMP3BCL2L1MAPTSMN1; SMN2
Biphenyl SCHEMBL9075352 0.88 ALDH1A1 (0.53) ALDH1A1MMP3BCL2L1MAPTSMN1; SMN2
Biphenyl SCHEMBL10474290 0.88 ALDH1A1 (0.53) ALDH1A1MMP3BCL2L1MAPTSMN1; SMN2
Phosphonic Acid SCHEMBL11578470 0.85 ALDH1A1 (0.52) ALDH1A1BCL2L1SMN1; SMN2MGLLMAPK1
Biphenyl SCHEMBL9009481 0.83 ALDH1A1 (0.47) ALDH1A1MMP3BCL2L1MAPTSMN1; SMN2
Biphenyl SCHEMBL9807554 0.83 ALDH1A1 (0.47) ALDH1A1MMP3BCL2L1MAPTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0469682-B1 Mesoporous crystalline compound of a tetravalent metal ENIRICERCHE SPA (IT) 1994-12-14 EP claimed
US-5246901-A POLYSULFONIC ACIDS CATALYTICA, INC. (US) 1993-09-21 US claimed
US-5166380-A MESOPOROUS CRYSTALLINE SOLID COMPOUND OF A DIPHOSPHONATE/PHOSPHITE OF A TETRAVALENT METAL, WITH A NARROW DISTRIBUTION OF MESOPORES ENIRICERCHE S.P.A. (IT) 1992-11-24 US claimed
EP-0469682-A1 Mesoporous crystalline compound of a tetravalent metal ENIRICERCHE S.p.A. (IT) 1992-02-05 EP claimed
EP-0416000-A4 POLYSULFONIC ACIDS 1991-12-04 EP claimed
EP-0416000-A1 POLYSULFONIC ACIDS CATALYTICA ASSOCIATES (US) 1991-03-13 EP claimed
WO-1989011485-A1 POLYSULFONIC ACIDS CATALYTICA ASSOCIATES (US) 1989-11-30 WO claimed
CN-113646009-A Compounds comprising anionic side groups and auxiliary groups for use as iron (III) MRI contrast agents 纽约州立大学研究基金会 2021-11-12 CN disclosed
EP-0492694-B1 Tetravalent metal diphosphonate-phosphite composition in microporous solid cristalline form, with a narrow micropore distribution ENIRICERCHE SPA (IT) 1996-10-16 EP disclosed
EP-0469682-B1 Mesoporous crystalline compound of a tetravalent metal ENIRICERCHE SPA (IT) 1994-12-14 EP disclosed
US-5290746-A Tetravalent metal diphosphonate-phosphite composition in microporous solid crystalline form, with a narrow micropore distribution ENIRICERCHE S.P.A. (IT) 1994-03-01 US disclosed
US-5166380-A MESOPOROUS CRYSTALLINE SOLID COMPOUND OF A DIPHOSPHONATE/PHOSPHITE OF A TETRAVALENT METAL, WITH A NARROW DISTRIBUTION OF MESOPORES ENIRICERCHE S.P.A. (IT) 1992-11-24 US disclosed
EP-0492694-A1 Tetravalent metal diphosphonate-phosphite composition in microporous solid cristalline form, with a narrow micropore distribution ENIRICERCHE S.p.A. (IT) 1992-07-01 EP disclosed
EP-0469682-A1 Mesoporous crystalline compound of a tetravalent metal ENIRICERCHE S.p.A. (IT) 1992-02-05 EP disclosed
US-5008468-A Sulfonic acid groups bonded to component containg tetravalent metal ion and group 5 element; used for olefin digomerization, polymerization, alkylation CATALYTICA, INC. (US) 1991-04-16 US disclosed
US-4868343-A METAL PHOSPHATE OR PHOSPHONATE CONTAINING SULFONIC ACID GROUPS, ETHERIFICATION, ISOMERIZATION CATALYTICA INC. (US) 1989-09-19 US disclosed