Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CTSS | P25774 | 4/20 | 0.38 |
| ▸ | CTSK | P43235 | 4/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.32 |
| ▸ | CTSG | P08311 | 1/20 | 0.32 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.32 |
| ▸ | CMA1 | P23946 | 1/20 | 0.32 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.31 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27916266 | 0.85 | CA1 (0.42) | MEN1KMT2ATSHRCA1CA2 | |
| SCHEMBL19773556 | 0.84 | MEN1 (0.40) | MEN1KMT2ATSHRCTSSCTSK | |
| SCHEMBL27916314 | 0.81 | ALDH1A1 (0.39) | MEN1KMT2ATSHRCA1CA2 | |
| SCHEMBL20093567 | 0.81 | MAPT (0.43) | MEN1KMT2ATSHRCA1CA2 | |
| SCHEMBL2276930 | 0.80 | MEN1 (0.42) | MEN1KMT2ATSHRCTSSCTSK | |
| SCHEMBL21166222 | 0.80 | MAPT (0.46) | MEN1KMT2ATSHRUSP2LMNA | |
| SCHEMBL21138599 | 0.78 | MEN1 (0.45) | MEN1KMT2ATSHRCTSSCTSK | |
| SCHEMBL14445397 | 0.77 | MAPT (0.47) | MEN1KMT2ATSHRUSP2LMNA | |
| SCHEMBL18612495 | 0.77 | MAPT (0.47) | MEN1KMT2ATSHRUSP2LMNA | |
| SCHEMBL28723450 | 0.77 | MAPT (0.47) | MEN1KMT2ATSHRUSP2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5532386-A | CATALYTIC CARBONIC ESTER AND A TERTIARY AMINE | BASF AKTIENGESELLSCHAFT (DE) | 1996-07-02 | — | — | US | disclosed |