SCHEMBL9009737

SCHEMBL9009737

O=C(O[C@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O)c1ccccc1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LGALS9 O00182 1/20 0.60
LGALS1 P09382 1/20 0.60
LGALS3 P17931 1/20 0.60
LGALS7; LGALS7B P47929 1/20 0.60
MAOB P27338 1/20 0.60
SYNJ2 O15056 2/20 0.51
KDM4E B2RXH2 1/20 0.51
ABL1 P00519 1/20 0.51
ALPL P05186 1/20 0.51
POLB P06746 1/20 0.51
ALPI P09923 1/20 0.51
GAA P10253 1/20 0.51
MAPT P10636 1/20 0.51
ALPG P10696 1/20 0.51
PABPC1 P11940 1/20 0.51
RECQL P46063 1/20 0.51
GALK1 P51570 1/20 0.51
CASP7 P55210 1/20 0.51
CASP6 P55212 1/20 0.51
MCL1 Q07820 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10524702 1.00 LGALS9 (0.60) LGALS9LGALS1LGALS3LGALS7; LGALS7BMAOB
SCHEMBL27486746 1.00 LGALS9 (0.60) LGALS9LGALS1LGALS3LGALS7; LGALS7BMAOB
SCHEMBL18094366 1.00 LGALS9 (0.60) LGALS9LGALS1LGALS3LGALS7; LGALS7BMAOB
SCHEMBL28090704 1.00 LGALS9 (0.60) LGALS9LGALS1LGALS3LGALS7; LGALS7BMAOB
SCHEMBL27777164 1.00 LGALS9 (0.60) LGALS9LGALS1LGALS3LGALS7; LGALS7BMAOB
SCHEMBL9451232 1.00 LGALS9 (0.60) LGALS9LGALS1LGALS3LGALS7; LGALS7BMAOB
SCHEMBL8762538 1.00 LGALS9 (0.60) LGALS9LGALS1LGALS3LGALS7; LGALS7BMAOB
SCHEMBL28140168 1.00 LGALS9 (0.60) LGALS9LGALS1LGALS3LGALS7; LGALS7BMAOB
Hydrochloric Acid SCHEMBL28255486 0.99 MAOB (0.59) LGALS9LGALS1LGALS3LGALS7; LGALS7BMAOB
SCHEMBL6570199 0.98 LGALS9 (0.61) LGALS9LGALS1LGALS3LGALS7; LGALS7BMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105461767-B A kind of chemical synthesis process of forsythin 富力 2019-03-12 CN disclosed
CN-106632518-B Preparation method of podophyllotoxin 4-OH derivative 江西师范大学 2018-08-10 CN disclosed
CN-107106709-A Radiopharmaceutical conjugates comprising a metabolite and an EPR agent targeting tumor cells 南非核能源有限公司 2017-08-29 CN disclosed
CN-106632518-A Preparation method of podophyllotoxin 4-OH derivative 江西师范大学 2017-05-10 CN disclosed
EP-0739333-A1 SELECTIVE ASYMMETRIC HYDROGENATION OF DEHYDROAMINO ACID DERIVATIVES USING RHODIUM AND IRIDIUM DIPHOSPHINITE CARBOHYDRATE CATALYST COMPOSITIONS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1996-10-30 EP disclosed
WO-1995018787-A1 SELECTIVE ASYMMETRIC HYDROGENATION OF DEHYDROAMINO ACID DERIVATIVES USING RHODIUM AND IRIDIUM DIPHOSPHINITE CARBOHYDRATE CATALYST COMPOSITIONS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1995-07-13 WO disclosed
EP-0553297-A1 PROCESS FOR THE PREPARATION OF GLYCOSYL PHOSPHATE TRIESTERS. DU PONT (US) 1993-08-04 EP disclosed
US-4871837-A DEPROTECTING SILYL-PROTECTED CARBOHYDRATES, AMINO ACIDS, PEPTIDES; LEWIS ACID HYDROLYSIS SYMBICOM AKTIEBOLAG (SE) 1989-10-03 US disclosed
EP-0239194-A2 Methods for preparing hydroxy compounds and intermediates SYMBICOM AB (SE) 1987-09-30 EP disclosed