Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GSK3A | P49840 | 2/20 | 0.39 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.38 |
| ▸ | HRAS | P01112 | 1/20 | 0.37 |
| ▸ | SLC29A1 | Q99808 | 2/20 | 0.36 |
| ▸ | HSPA2 | P54652 | 1/20 | 0.36 |
| ▸ | DNPH1 | O43598 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2955999 | 0.83 | BCHE (0.42) | LMNABCHE | |
| SCHEMBL5496887 | 0.76 | BCHE (0.37) | BCHE | |
| SCHEMBL2045673 | 0.76 | EGFR (0.41) | LMNABCHESLC29A1 | |
| SCHEMBL1140703 | 0.76 | EGFR (0.41) | LMNABCHESLC29A1 | |
| SCHEMBL13238881 | 0.76 | EGFR (0.41) | LMNABCHESLC29A1 | |
| SCHEMBL9689709 | 0.75 | ABCB1 (0.38) | ABCB1LMNAGSK3ARPS6KA3MAPK14 | |
| SCHEMBL2950104 | 0.75 | EGFR (0.40) | LMNABCHESLC29A1 | |
| SCHEMBL2950100 | 0.75 | EGFR (0.40) | LMNABCHESLC29A1 | |
| SCHEMBL9687934 | 0.75 | SLC29A1 (0.43) | BCHESLC29A1DNPH1 | |
| SCHEMBL9223633 | 0.74 | DUT (0.48) | BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0504868-B1 | Method of manufacturing 2'-3'-dideoxy-2',3'.didehydronucleosides | JAPAN TOBACCO INC (JP) | 1996-11-06 | — | — | EP | disclosed |
| US-5264561-A | Reaction with an acid anhydride in the presence of a catalyst such as zirconium oxide, titanium oxide, alumina and acetic anhydride | JAPAN TOBACCO INC. (JP) | 1993-11-23 | — | — | US | disclosed |
| EP-0504868-A1 | Method of manufacturing 2'-3'-dideoxy-2',3'.didehydronucleosides | JAPAN TOBACCO INC. (JP) | 1992-09-23 | — | — | EP | disclosed |
| EP-0493602-A1 | PROCESS FOR PRODUCING 2',3'-DIDEOXY-2',3'-DIDEHYDRONUCLEOSIDE | YUKI GOSEI KOGYO CO., LTD. (JP) | 1992-07-08 | — | — | EP | disclosed |