Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.32 |
| ▸ | RXRA | P19793 | 1/20 | 0.32 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.32 |
| ▸ | RXRB | P28702 | 1/20 | 0.32 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.32 |
| ▸ | RXRG | P48443 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17221092 | 0.76 | ALDH1A1 (0.33) | ALDH1A1GABRA1TSHRGABRG2RXRA | |
| SCHEMBL1058952 | 0.76 | — | — | |
| SCHEMBL1058953 | 0.76 | — | — | |
| SCHEMBL9307214 | 0.72 | — | — | |
| SCHEMBL11313904 | 0.72 | ALDH1A1 (0.36) | ALDH1A1GABRA1TSHRGABRG2RXRA | |
| Methacrylic Acid SCHEMBL15638063 | 0.71 | ALDH1A1 (0.31) | ALDH1A1GABRA1TSHRGABRG2RXRA | |
| SCHEMBL18543812 | 0.67 | GRIK1 (0.39) | ALDH1A1GABRA1TSHRGABRG2RXRA | |
| SCHEMBL101807 | 0.67 | GRIK1 (0.43) | ALDH1A1GABRA1TSHRGABRG2RXRA | |
| SCHEMBL101809 | 0.67 | GRIK1 (0.43) | ALDH1A1GABRA1TSHRGABRG2RXRA | |
| SCHEMBL1244752 | 0.67 | GRIK1 (0.39) | ALDH1A1GABRA1TSHRGABRG2RXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0518724-B1 | Dithiane substituted propenals and process for their preparation | OREAL (FR) | 1996-11-13 | — | — | EP | disclosed |
| EP-0518722-B1 | Dithiane substituted retinoides, their use, process of their preparation, cosmetic and pharmaceutical compositions containing them and their use in therapeutics | OREAL (FR) | 1996-10-23 | — | — | EP | disclosed |
| EP-0518724-A1 | Dithiane substituted propenals and process for their preparation | L'OREAL (FR) | 1992-12-16 | — | — | EP | disclosed |
| EP-0518722-A1 | Dithiane substituted retinoides, their use, process of their preparation, cosmetic and pharmaceutical compositions containing them and their use in therapeutics | L'OREAL (FR) | 1992-12-16 | — | — | EP | disclosed |