Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 1/20 | 0.52 |
| ▸ | AURKA | O14965 | 1/20 | 0.49 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | TSHR | P16473 | 4/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.39 |
| ▸ | NSD2 | O96028 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | TDP2 | O95551 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | TDO2 | P48775 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28750494 | 0.81 | TTR (0.43) | TTRAURKAAURKBALDH1A1TSHR | |
| SCHEMBL668652 | 0.77 | TTR (0.54) | TTRAURKAAURKBALDH1A1TSHR | |
| SCHEMBL9009874 | 0.77 | TTR (0.51) | TTRAURKAAURKBALDH1A1TSHR | |
| SCHEMBL28345568 | 0.76 | AURKA (0.60) | TTRAURKAAURKBALDH1A1HSD17B10 | |
| SCHEMBL28407130 | 0.74 | TTR (0.52) | TTRAURKAAURKBALDH1A1TSHR | |
| SCHEMBL11430380 | 0.74 | TTR (0.52) | TTRAURKAAURKBALDH1A1TSHR | |
| SCHEMBL20499713 | 0.74 | CYP1A2 (0.37) | TTRAURKAAURKBALDH1A1TSHR | |
| SCHEMBL2524546 | 0.74 | TSHR (0.48) | TTRAURKAAURKBTSHRTDP1 | |
| SCHEMBL9813360 | 0.73 | AURKA (0.72) | TTRAURKAAURKBALDH1A1TSHR | |
| SCHEMBL5711912 | 0.73 | AURKA (0.77) | TTRAURKAAURKBALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0472968-B1 | Granular type reactive dye compositions and methods for dyeing and printing cellulose fibers using the same | SUMITOMO CHEMICAL CO (JP) | 1996-11-06 | — | — | EP | disclosed |