Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 1/20 | 0.60 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.60 |
| ▸ | TTR | P02766 | 1/20 | 0.51 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.47 |
| ▸ | MPL | P40238 | 4/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | NT5E | P21589 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CTRC | Q99895 | 1/20 | 0.37 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.36 |
| ▸ | NQO1 | P15559 | 1/20 | 0.36 |
| ▸ | COMT | P21964 | 1/20 | 0.36 |
| ▸ | NSD2 | O96028 | 1/20 | 0.35 |
| ▸ | MMP14 | P50281 | 1/20 | 0.35 |
| ▸ | CASP6 | P55212 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9331572 | 0.88 | AURKB (0.65) | AURKAAURKBTTRNR4A1MPL | |
| SCHEMBL5246088 | 0.85 | AURKB (0.53) | AURKAAURKBTTRNR4A1MPL | |
| SCHEMBL3211377 | 0.79 | AURKB (0.87) | AURKAAURKBTTRNR4A1CYP1A2 | |
| SCHEMBL4810070 | 0.76 | MPL (0.58) | MPLCDK2CYP2D6CTRCHKDC1 | |
| SCHEMBL9009888 | 0.76 | TTR (0.52) | AURKAAURKBTTRNR4A1NT5E | |
| SCHEMBL11431367 | 0.76 | AURKA (0.66) | AURKAAURKBTTRNR4A1CYP1A2 | |
| SCHEMBL30097938 | 0.76 | AURKB (1.00) | AURKAAURKBTTRNR4A1MPL | |
| SCHEMBL28248814 | 0.76 | TTR (0.61) | AURKAAURKBTTRALDH1A1HSD17B10 | |
| SCHEMBL156516 | 0.76 | AURKB (1.00) | AURKAAURKBTTRNR4A1MPL | |
| SCHEMBL11047153 | 0.75 | AURKA (0.45) | AURKAAURKBTTRCYP1A2NT5E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106232214-B | Composite polyamide membrane post-treated with nitrous acid | 陶氏环球技术有限责任公司 | 2021-01-15 | — | — | CN | disclosed |
| CN-105848758-B | Separation of hydrocarbons from aqueous mixtures using fouling resistant reverse osmosis membranes | 陶氏环球技术有限责任公司 | 2020-01-17 | — | — | CN | disclosed |