SCHEMBL900994

SCHEMBL900994

CC1=CCC2C(=O)CCC(C)(C)C2C1

nearest known ligand 0.36

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.32
GAA P10253 2/20 0.31
TSHR P16473 1/20 0.31
CNR1 P21554 1/20 0.31
MEN1 O00255 2/20 0.30
KMT2A Q03164 2/20 0.30
CNR2 P34972 1/20 0.30
PPARA Q07869 1/20 0.30
USP2 O75604 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15131693 0.87 CNR1 (0.36) CYP3A4GAATSHRCNR1CNR2
SCHEMBL12687625 0.70 CYP3A4 (0.39) CYP3A4
SCHEMBL15123858 0.66 CYP3A4 (0.42) CYP3A4KMT2ACNR2PPARA
Carene SCHEMBL19922327 0.64 CNR1 (0.37) TSHRCNR1CNR2
Carene SCHEMBL31500923 0.64 CNR1 (0.37) TSHRCNR1CNR2
Carene SCHEMBL16268963 0.64 CNR1 (0.37) TSHRCNR1CNR2
Carene SCHEMBL112444 0.64 CNR1 (0.37) TSHRCNR1CNR2
Carene SCHEMBL1532729 0.64 CNR1 (0.37) TSHRCNR1CNR2
SCHEMBL9502227 0.63 TSHR (0.39) GAATSHRCNR1MEN1KMT2A
Hydrochloric Acid SCHEMBL8874614 0.63 CYP3A4 (0.34) CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2622051-B1 4,4-DIMETHYL-DECAL-1-ONE OR -1-OL DERIVATIVES AS PERFUMING INGREDIENTS FIRMENICH & CIE (CH) 2014-07-09 EP disclosed
EP-2622051-B1 4,4-DIMETHYL-DECAL-1-ONE OR -1-OL DERIVATIVES AS PERFUMING INGREDIENTS FIRMENICH & CIE (CH) 2014-07-09 EP disclosed
US-8697626-B2 4,4-dimethyl-decal-1-one or -1-OL derivatives as perfuming ingredients FIRMENICH SA (CH) 2014-04-15 US disclosed
EP-2622051-A1 4,4-DIMETHYL-DECAL-1-ONE OR -1-OL DERIVATIVES AS PERFUMING INGREDIENTS Firmenich SA (CH) 2013-08-07 EP disclosed
US-20130190218-A1 4,4-DIMETHYL-DECAL-1-ONE OR -1-OL DERIVATIVES AS PERFUMING INGREDIENTS FIRMENICH SA 2013-07-25 US disclosed
US-20130190218-A1 4,4-DIMETHYL-DECAL-1-ONE OR -1-OL DERIVATIVES AS PERFUMING INGREDIENTS FIRMENICH SA 2013-07-25 US disclosed
US-20130190218-A1 4,4-DIMETHYL-DECAL-1-ONE OR -1-OL DERIVATIVES AS PERFUMING INGREDIENTS FIRMENICH SA 2013-07-25 US disclosed
WO-2012041820-A1 4,4-DIMETHYL-DECAL-1-ONE OR -1-OL DERIVATIVES AS PERFUMING INGREDIENTS FIRMENICH SA (CH) 2012-04-05 WO disclosed