SCHEMBL9502227

SCHEMBL9502227

CC1=CCC2C(=O)NC(=O)C2C1

nearest known ligand 0.45

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.39
GAA P10253 2/20 0.39
ALDH1A1 P00352 6/20 0.38
PKM P14618 1/20 0.38
KMT2A Q03164 4/20 0.37
MEN1 O00255 2/20 0.37
USP2 O75604 1/20 0.37
TDP1 Q9NUW8 2/20 0.36
POLB P06746 2/20 0.36
APEX1 P27695 1/20 0.36
RXFP1 Q9HBX9 1/20 0.35
HPGD P15428 1/20 0.35
CNR1 P21554 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20747450 0.75 ALDH1A1 (0.49) ALDH1A1PKM
SCHEMBL9580701 0.73 ALDH1A1 (0.34) ALDH1A1PKM
SCHEMBL10400960 0.72 CRBN (0.36) TSHRALDH1A1PKMHPGD
SCHEMBL2265750 0.71 FNTA (0.49) TSHRGAAALDH1A1KMT2AMEN1
SCHEMBL2265747 0.71 FNTA (0.49) TSHRGAAALDH1A1KMT2AMEN1
SCHEMBL354462 0.71 FNTA (0.49) TSHRGAAALDH1A1KMT2AMEN1
SCHEMBL11542394 0.71 TSHR (0.39) TSHRGAAALDH1A1KMT2AMEN1
SCHEMBL1221247 0.69 ALDH1A1 (0.32) ALDH1A1PKM
SCHEMBL9906960 0.69 ALDH1A1 (0.51) TSHRGAAALDH1A1KMT2AMEN1
SCHEMBL2547401 0.69 PDE4A (0.38) TSHRALDH1A1KMT2ATDP1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0355676-B1 USE OF COPOLYMERS OF HIGHER ALKYL ACRYLATES WITH N-CONTAINING OLEFINS AS LEVELLING AGENTS FOR POWDER COATINGS Henkel Kommanditgesellschaft auf Aktien (DE) 1993-04-28 EP disclosed
US-5047259-A For powder coating; long chain alkyl acrylates; solventless paint systems HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1991-09-10 US disclosed
US-5006621-A Co-polymers of long chain alkyl acrylates with N-containing olefins and their use as flow improvers for crude oils HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1991-04-09 US disclosed
EP-0399351-A2 Epoxy resin and water borne coatings therefrom THE DOW CHEMICAL COMPANY (US) 1990-11-28 EP disclosed
US-4946911-A CONTAINING UNSATURATED IMIDE THE DOW CHEMICAL COMPANY (US) 1990-08-07 US disclosed
EP-0355676-A2 Use of copolymers of higher alkyl acrylates with N-containing olefins as levelling agents for powder coatings Henkel Kommanditgesellschaft auf Aktien (DE) 1990-02-28 EP disclosed
EP-0334155-A1 Copolymers of long-chain alkyl acrylates with n-containing olefins, process for their preparation and their use as flow improvers in crude oils Henkel Kommanditgesellschaft auf Aktien (DE) 1989-09-27 EP disclosed