SCHEMBL9010028

SCHEMBL9010028

CC(C)OC(=O)C1C=CCCC1C(N)=O

nearest known ligand 0.38

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.38
MAPT P10636 1/20 0.35
POLB P06746 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
EPHX1 P07099 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2275352 0.89 MAPT (0.37) GAAMAPTPOLBNPSR1
SCHEMBL6318600 0.86 MAPT (0.36) MAPTPOLBNPSR1
SCHEMBL9010032 0.78 ALOX15 (0.43) GAAMAPT
SCHEMBL6219581 0.77 MAPT (0.36) MAPTEPHX1
SCHEMBL9009960 0.76 EPHX1 (0.34) MAPTEPHX1
SCHEMBL13571631 0.75 MAPT (0.35) MAPT
SCHEMBL10385867 0.75 MAPT (0.35) GAAMAPT
SCHEMBL1169445 0.75 POLB (0.44) GAAPOLBNPSR1
SCHEMBL9010026 0.75 TSHR (0.35) MAPTPOLB
SCHEMBL9009964 0.75 MAPT (0.35) GAAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0741131-A1 N-PHENYLTETRAHYDROPHTHALAMIC ACID DERIVATIVE, PROCESS FOR PRODUCING THE SAME, AND HERBICIDE CONTAINING THE SAME AS ACTIVE INGREDIENT CENTRAL GLASS COMPANY, LIMITED (JP) 1996-11-06 EP disclosed