Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.31 |
| ▸ | AURKA | O14965 | 1/20 | 0.30 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.30 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.30 |
| ▸ | KDR | P35968 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8460029 | 0.84 | BRD4 (0.37) | BRD4AOC3AURKAAURKBCHEK1 | |
| Hydrochloric Acid SCHEMBL9010009 | 0.72 | BRD4 (0.34) | BRD4AOC3AURKAAURKBCHEK1 | |
| Hydrochloric Acid SCHEMBL9010016 | 0.70 | — | — | |
| Hydrochloric Acid SCHEMBL8462951 | 0.65 | AOC3 (0.47) | BRD4AOC3AURKAAURKBCHEK1 | |
| Hydrochloric Acid SCHEMBL8459863 | 0.63 | BRD4 (0.33) | BRD4AOC3AURKAAURKB | |
| Hydrochloric Acid SCHEMBL9010289 | 0.63 | KDM4E (0.33) | BRD4AOC3AURKACHEK1KDR | |
| Hydrochloric Acid SCHEMBL8463556 | 0.62 | AOC3 (0.42) | BRD4AOC3AURKAAURKBCHEK1 | |
| Hydrochloric Acid SCHEMBL8459502 | 0.61 | KDM4E (0.36) | BRD4AOC3 | |
| Hydrochloric Acid SCHEMBL9010040 | 0.60 | AHR (0.38) | — | |
| Hydrochloric Acid SCHEMBL8463906 | 0.59 | BRD4 (0.37) | BRD4AOC3AURKAAURKBCHEK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0741145-A1 | Olefin polymerization catalyst and process for producing polyolefin using the same | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-11-06 | — | — | EP | disclosed |