Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRZ1 | P23471 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL900918 | 0.87 | KDM4E (0.35) | PTPRZ1KDM4EALDH1A1TDP1PTPN1 | |
| SCHEMBL12474324 | 0.83 | KDM4E (0.39) | PTPRZ1KDM4EALDH1A1TDP1PTPN1 | |
| SCHEMBL900575 | 0.74 | IDO1 (0.32) | — | |
| SCHEMBL5544527 | 0.74 | PTPRZ1 (0.53) | PTPRZ1KDM4EALDH1A1TDP1PTPN1 | |
| SCHEMBL8714549 | 0.73 | IDO1 (0.47) | KDM4EALDH1A1KCNH2SMN1; SMN2CA2 | |
| SCHEMBL12474320 | 0.73 | KDM4E (0.39) | PTPRZ1KDM4EALDH1A1TDP1PTPN1 | |
| SCHEMBL17288972 | 0.72 | FFAR4 (0.40) | PTPRZ1KDM4EALDH1A1TDP1PTPN1 | |
| SCHEMBL12474332 | 0.72 | KDM4E (0.36) | PTPRZ1KDM4EALDH1A1TDP1PTPN1 | |
| SCHEMBL900287 | 0.71 | HTR2A (0.34) | — | |
| SCHEMBL900895 | 0.71 | TAAR1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2621922-A1 | A PROCESS FOR THE SYNTHESIS OF THIO-TRIAZOLO-GROUP CONTAINING COMPOUNDS | BASF SE (DE) | 2013-08-07 | — | — | EP | disclosed |
| WO-2012041858-A1 | A PROCESS FOR THE SYNTHESIS OF THIO-TRIAZOLO-GROUP CONTAINING COMPOUNDS | BASF SE (DE) | 2012-04-05 | — | — | WO | disclosed |