Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 3/20 | 0.34 |
| ▸ | HTR2C | P28335 | 2/20 | 0.34 |
| ▸ | HTR2B | P41595 | 2/20 | 0.34 |
| ▸ | DDR1 | Q08345 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL900575 | 0.87 | IDO1 (0.32) | HTR2AHTR2CHTR2B | |
| SCHEMBL900795 | 0.83 | HTR2A (0.34) | HTR2AHTR2CHTR2BDDR1 | |
| SCHEMBL17288665 | 0.78 | FFAR4 (0.41) | HTR2AHTR2CHTR2B | |
| SCHEMBL900569 | 0.77 | FFAR4 (0.36) | — | |
| SCHEMBL12474365 | 0.74 | PDE2A (0.38) | HTR2AHTR2CHTR2B | |
| SCHEMBL16960851 | 0.73 | PSEN1 (0.39) | — | |
| SCHEMBL12474346 | 0.73 | IDO1 (0.35) | HTR2AHTR2CHTR2B | |
| SCHEMBL900763 | 0.72 | HTR2A (0.35) | HTR2AHTR2CHTR2BDDR1 | |
| SCHEMBL901039 | 0.71 | PTPRZ1 (0.36) | — | |
| SCHEMBL900918 | 0.71 | KDM4E (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2621922-A1 | A PROCESS FOR THE SYNTHESIS OF THIO-TRIAZOLO-GROUP CONTAINING COMPOUNDS | BASF SE (DE) | 2013-08-07 | — | — | EP | disclosed |
| WO-2012041858-A1 | A PROCESS FOR THE SYNTHESIS OF THIO-TRIAZOLO-GROUP CONTAINING COMPOUNDS | BASF SE (DE) | 2012-04-05 | — | — | WO | disclosed |