Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | HTT | P42858 | 2/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.54 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.41 |
| ▸ | TUBB | P07437 | 1/20 | 0.41 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.41 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.41 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.41 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.41 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.41 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.41 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.41 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.41 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.41 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10711500 | 0.87 | HTT (0.54) | MEN1KMT2AHTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL8106191 | 0.84 | HTT (0.70) | MEN1KMT2AHTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL20382948 | 0.83 | HTT (0.68) | MEN1KMT2AHTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL3358984 | 0.80 | HTT (0.75) | MEN1KMT2AHTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL8100651 | 0.80 | HTT (0.58) | MEN1KMT2AHTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL8119717 | 0.80 | HTT (0.58) | MEN1KMT2AHTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL9515266 | 0.80 | HTT (0.67) | MEN1KMT2AHTTSMN1; SMN2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL8092524 | 0.79 | HTT (0.57) | MEN1KMT2AHTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL8122829 | 0.79 | HTT (0.73) | MEN1KMT2AHTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL3357703 | 0.79 | HTT (0.73) | MEN1KMT2AHTTSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0305646-B1 | 3-Hydroxypyrid-4-ones and pharmaceutical compositions | BRITISH TECH GROUP (GB) | 1996-11-13 | — | — | EP | disclosed |