SCHEMBL8122829

SCHEMBL8122829

Cc1c(OCc2ccccc2)c(=O)ccn1CCN

nearest known ligand 0.73

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
HTT P42858 3/20 0.73
SMN1; SMN2 Q16637 3/20 0.73
MEN1 O00255 3/20 0.73
KMT2A Q03164 3/20 0.73
ALDH1A1 P00352 2/20 0.73
HPGD P15428 1/20 0.73
NPC1 O15118 1/20 0.67
NPSR1 Q6W5P4 2/20 0.65
LMNA P02545 2/20 0.48
POLB P06746 1/20 0.48
GAA P10253 1/20 0.48
MAPT P10636 1/20 0.47
MAPK14 Q16539 3/20 0.45
KDM4E B2RXH2 1/20 0.43
TP53 P04637 1/20 0.43
CYP2D6 P10635 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3289112 0.92 HTT (0.70) HTTSMN1; SMN2MEN1KMT2AALDH1A1
SCHEMBL16882316 0.89 SMN1; SMN2 (0.73) HTTSMN1; SMN2MEN1KMT2AALDH1A1
SCHEMBL13003556 0.89 HTT (0.77) HTTSMN1; SMN2MEN1KMT2AALDH1A1
SCHEMBL15020751 0.88 HTT (0.64) HTTSMN1; SMN2MEN1KMT2AALDH1A1
SCHEMBL3358984 0.88 HTT (0.75) HTTSMN1; SMN2MEN1KMT2AALDH1A1
SCHEMBL30669320 0.88 HTT (0.75) HTTSMN1; SMN2MEN1KMT2AALDH1A1
SCHEMBL8106191 0.87 HTT (0.70) HTTSMN1; SMN2MEN1KMT2AALDH1A1
SCHEMBL3357703 0.86 HTT (0.73) HTTSMN1; SMN2MEN1KMT2AALDH1A1
SCHEMBL28377462 0.86 HTT (0.54) HTTSMN1; SMN2MEN1KMT2AALDH1A1
SCHEMBL20382948 0.86 HTT (0.68) HTTSMN1; SMN2MEN1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260053929-A1 METAL CHELATING COMPOSITIONS AND METHODS FOR CONTROLLING THE GROWTH OR ACTIVITIES OF A LIVING CELL OR ORGANISM CHELATION PARTNERS INCORPORATED (CA) 2026-02-26 US disclosed
CN-115260162-B 3-Hydroxy-4-pyridone-ciprofloxacin coupling, preparation method and application thereof 浙江大学 2024-07-05 CN disclosed
US-12024490-B2 Polymeric metal chelating compositions and methods of preparing same for controlling growth and activities of living cells and organisms for therapeutic use in treating diseases in animals, fish or humans CHELATION PARTNERS INCORPORATED (CA) 2024-07-02 US disclosed
CN-117338950-A Polymer material for reducing cardiac toxicity of anthracycline chemotherapeutics and application thereof 天津大学 2024-01-05 CN disclosed
CN-116425718-A Derivatives of phthalimido-3-hydroxypyridine-4-one and application thereof 浙江工业大学 2023-07-14 CN disclosed
WO-2023070780-A1 MONOAMINE OXIDASE B INHIBITOR HAVING POTENTIAL IRON CHELATING ACTIVITY AND USE THEREOF 浙江工业大学 2023-05-04 WO disclosed
CN-115260162-A 3-hydroxy-4-pyridone-ciprofloxacin coupling compound and preparation method and application thereof 浙江大学 2022-11-01 CN disclosed
CN-114149417-A Monoamine oxidase B inhibitor with potential iron chelation activity and application thereof 浙江工业大学 2022-03-08 CN disclosed
US-20220002250-A1 POLYMERIC METAL CHELATING COMPOSITIONS AND METHODS OF PREPARING SAME FOR CONTROLLING GROWTH AND ACTIVITIES OF LIVING CELLS AND ORGANISMS FOR THERAPEUTIC USE IN TREATING DISEASES IN ANIMALS, FISH OR HUMANS JUBILANT CHEMSYS LTD. (IN) 2022-01-06 US disclosed
US-20220002250-A1 POLYMERIC METAL CHELATING COMPOSITIONS AND METHODS OF PREPARING SAME FOR CONTROLLING GROWTH AND ACTIVITIES OF LIVING CELLS AND ORGANISMS FOR THERAPEUTIC USE IN TREATING DISEASES IN ANIMALS, FISH OR HUMANS JUBILANT CHEMSYS LTD. (IN) 2022-01-06 US disclosed
EP-3504188-A1 POLYMERIC METAL CHELATING COMPOSITIONS AND METHODS OF PREPARING SAME FOR CONTROLLING GROWTH AND ACTIVITIES OF LIVING CELLS AND ORGANISMS Chelation Partners Incorporated (CA) 2019-07-03 EP disclosed
US-20190169126-A1 POLYMERIC METAL CHELATING COMPOSITIONS AND METHODS OF PREPARING SAME FOR CONTROLLING GROWTH AND ACTIVITIES OF LIVING CELLS AND ORGANISMS CHELATION PARTNERS INCORPORATED (CA) 2019-06-06 US disclosed
US-20190169126-A1 POLYMERIC METAL CHELATING COMPOSITIONS AND METHODS OF PREPARING SAME FOR CONTROLLING GROWTH AND ACTIVITIES OF LIVING CELLS AND ORGANISMS CHELATION PARTNERS INCORPORATED (CA) 2019-06-06 US disclosed
WO-2018035613-A1 POLYMERIC METAL CHELATING COMPOSITIONS AND METHODS OF PREPARING SAME FOR CONTROLLING GROWTH AND ACTIVITIES OF LIVING CELLS AND ORGANISMS CHELATION PARTNERS INCORPORATED (CA) 2018-03-01 WO disclosed
US-20160038604-A1 METAL CHELATING COMPOSITIONS AND METHODS FOR CONTROLLING THE GROWTH OR ACTIVITIES OF A LIVING CELL OR ORGANISM CHELATION PARTNERS INCORPORATED 2016-02-11 US disclosed
US-20160038604-A1 METAL CHELATING COMPOSITIONS AND METHODS FOR CONTROLLING THE GROWTH OR ACTIVITIES OF A LIVING CELL OR ORGANISM CHELATION PARTNERS INCORPORATED 2016-02-11 US disclosed
EP-2717886-A1 METAL CHELATING COMPOSITIONS AND METHODS FOR CONTROLLING THE GROWTH OR ACTIVITIES OF A LIVING CELL OR ORGANISM Chelation Partners Incorporated (CA) 2014-04-16 EP disclosed
WO-2012167368-A1 METAL CHELATING COMPOSITIONS AND METHODS FOR CONTROLLING THE GROWTH OR ACTIVITIES OF A LIVING CELL OR ORGANISM CHELATION PARTNERS INCORPORATED (CA) 2012-12-13 WO disclosed
EP-1006112-A1 3-Hydroxy-2(1H)-pyridinone or 3-hydroxy-4(1H)-pyridinone derivatives useful as reactive oxygen species (ROS) scavengers Cerebrus Pharmaceuticals Limited (GB) 2000-06-07 EP disclosed
EP-1006108-A1 3-Hydroxy-2(1H)-pyridinone or 3-hydroxy-4(1H)-pyridinone derivatives useful as reactive oxygen species (ROS) scavengers Cerebrus Pharmaceuticals Limited (GB) 2000-06-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220002250-A1 POLYMERIC METAL CHELATING COMPOSITIONS AND METHODS OF PREPARING SAME FOR CONTROLLING GROWTH AND ACTIVITIES OF LIVING CELLS AND ORGANISMS FOR THERAPEUTIC USE IN TREATING DISEASES IN ANIMALS, FISH OR HUMANS TFRC, HMBS, PICALM HTT 1484/4885SMN1; SMN2 812/4885MEN1 2264/4885
US-12024490-B2 Polymeric metal chelating compositions and methods of preparing same for controlling growth and activities of living cells and organisms for therapeutic use in treating diseases in animals, fish or humans TFRC, HMBS, PICALM HTT 1484/4885SMN1; SMN2 812/4885MEN1 2264/4885
US-20190169126-A1 POLYMERIC METAL CHELATING COMPOSITIONS AND METHODS OF PREPARING SAME FOR CONTROLLING GROWTH AND ACTIVITIES OF LIVING CELLS AND ORGANISMS PICALM, HMBS, TFRC HTT 3362/4885SMN1; SMN2 2683/4885MEN1 1739/4885
US-20260053929-A1 METAL CHELATING COMPOSITIONS AND METHODS FOR CONTROLLING THE GROWTH OR ACTIVITIES OF A LIVING CELL OR ORGANISM HAMP, SLC40A1, TFRC HTT 3080/4885SMN1; SMN2 1929/4885MEN1 556/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.