SCHEMBL901046

SCHEMBL901046

O=C(O)c1ccc(O)c(-c2ccccc2)c1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BACE1 P56817 2/20 0.58
POLB P06746 2/20 0.57
KDM4E B2RXH2 2/20 0.57
GAA P10253 2/20 0.57
CA12 O43570 1/20 0.57
CA1 P00915 1/20 0.57
CA2 P00918 1/20 0.57
MAPT P10636 1/20 0.57
CA4 P22748 1/20 0.57
CA6 P23280 1/20 0.57
PTGS2 P35354 1/20 0.57
CA7 P43166 1/20 0.57
CA9 Q16790 1/20 0.57
CA14 Q9ULX7 1/20 0.57
L3MBTL1 Q9Y468 1/20 0.57
TTR P02766 2/20 0.53
KMO O15229 1/20 0.52
PTPRC P08575 2/20 0.52
EGFR P00533 1/20 0.52
ALDH1A1 P00352 3/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29772126 1.00 BACE1 (0.58) BACE1POLBKDM4EGAACA12
SCHEMBL10479736 0.98 BACE1 (0.56) BACE1POLBKDM4EGAACA12
SCHEMBL3221434 0.96 EGFR (0.58) BACE1POLBKDM4EGAACA12
SCHEMBL8658097 0.88 BACE1 (0.58) BACE1MAPTPTGS2L3MBTL1EGFR
Terephthalic Acid SCHEMBL9857404 0.87 EGFR (0.56) BACE1POLBKDM4EGAACA12
Vanillic Acid SCHEMBL1434414 0.86 HTT (0.73) CA12CA1CA2CA4CA6
SCHEMBL3663963 0.86 POLB (0.59) BACE1POLBKDM4EGAACA12
SCHEMBL28942902 0.85 CA12 (0.70) POLBKDM4EGAACA12CA1
SCHEMBL29593590 0.85 CA12 (0.70) POLBKDM4EGAACA12CA1
SCHEMBL9511744 0.85 MAPT (0.57) BACE1KDM4EMAPTEGFRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 279 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5746949-A Polarizer films comprising aromatic liquid crystalline polymers comprising dichroic dyes in their main chains HOECHST CELANESE CORP. (US) 1998-05-05 US claimed
WO-1997019374-A1 POLARIZER FILMS COMPRISING AROMATIC LIQUID CRYSTALLINE POLYMERS COMPRISING DICHROIC DYES IN THEIR MAIN CHAINS HOECHST CELANESE CORPORATION (US) 1997-05-29 WO claimed
EP-0556021-A1 Liquid crystalline polyester compositions and method for making GENERAL ELECTRIC COMPANY (US) 1993-08-18 EP claimed
US-4889911-A ESTERIFICATION, ESTER INTERCHANGE; CATALYSIS WITH HETEROCYCLIC NITROGEN COMPOUND BAYER AKTIENGESELLSCHAFT (DE) 1989-12-26 US claimed
US-4873367-A CARBONATION OF A 2-PHENYLPHENOL ALKALI METAL SALT GENERAL ELECTRIC COMPANY (US) 1989-10-10 US claimed
JP-1289827-A None JP disclosed
JP-1113339-A None JP disclosed
JP-1113340-A None JP disclosed
JP-1168640-A None JP disclosed
CN-114853992-B Soluble low dielectric constant low dielectric loss flame-retardant wholly aromatic copolyester and preparation method and application thereof 四川大学 2024-04-26 CN disclosed
US-11866584-B2 High-refractive-index composition, high-refractive-index film, and method for manufacturing high-refractive-index film LG CHEM, LTD. (KR) 2024-01-09 US disclosed
CN-114853992-A Soluble low-dielectric-constant low-dielectric-loss flame-retardant full-aromatic copolyester and preparation method and application thereof 四川大学 2022-08-05 CN disclosed
US-4299756-A FIBERS, FILMS, AND MOLDING MATERIALS CELANESE CORPORATION (US) 1981-11-10 US disclosed
US-4279803-A Polyester of phenyl-4-hydroxybenzoic acid and 4-hydroxybenzoic acid and/or 6-hydroxy-2-naphthoic acid capable of forming an anisotropic melt CELANESE CORPORATION (US) 1981-07-21 US disclosed
EP-0024499-A1 Biaxially oriented wholly aromatic polyester film and process for producing same TEIJIN LIMITED (JP) 1981-03-11 EP disclosed
US-4236732-A COLOR DEVELOPING LAYER CONTAINING PARTICLES OF A CHROMOGENIC MATERIAL, AN ACCEPTOR AND A HEAT FUSIBLE MATERIAL KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1980-12-02 US disclosed
US-4228222-A COLOR DEVELOPING LAYER INCLUDING WATER SOLUBLE RESIN AS BINDER KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1980-10-14 US disclosed
US-4168845-A Heat-sensitive record material KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1979-09-25 US disclosed
US-4134847-A HOMOGENIZING AN AROMATIC CARBOXYLIC ACID-POLYMER-METAL CARBONATE OR OXIDE MELT KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1979-01-16 US disclosed
US-4046941-A PRESSURE SENSITIVE COPYING SANKO CHEMICAL COMPANY LTD. (JA) 1977-09-06 US disclosed