Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 1/20 | 0.50 |
| ▸ | JAK3 | P52333 | 1/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | BTK | Q06187 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.41 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1969115 | 0.81 | JAK2 (0.53) | JAK2JAK3RXFP1ALDH1A1TSHR | |
| SCHEMBL14130143 | 0.81 | JAK2 (0.53) | JAK2JAK3RXFP1ALDH1A1TSHR | |
| SCHEMBL7419149 | 0.78 | JAK2 (0.53) | JAK2JAK3RXFP1ALDH1A1TSHR | |
| SCHEMBL5063232 | 0.78 | JAK2 (0.50) | JAK2JAK3RXFP1ALDH1A1TSHR | |
| SCHEMBL18094323 | 0.76 | JAK2 (0.51) | JAK2JAK3RXFP1ALDH1A1MAPK1 | |
| SCHEMBL7415910 | 0.73 | JAK2 (0.48) | JAK2JAK3RXFP1ALDH1A1MAPK1 | |
| SCHEMBL31157850 | 0.72 | RXFP1 (0.52) | RXFP1ALDH1A1MAPK1LMNAKDM4E | |
| SCHEMBL1363765 | 0.72 | RXFP1 (0.61) | JAK2JAK3RXFP1ALDH1A1MAPK1 | |
| SCHEMBL18772204 | 0.72 | JAK2 (0.47) | JAK2JAK3BTKALDH1A1L3MBTL1 | |
| SCHEMBL7078820 | 0.71 | JAK2 (0.47) | JAK2JAK3RXFP1ALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5556873-A | AGRICULTURAL PESTICIDES | RHONE-POULENC INC. (US) | 1996-09-17 | — | — | US | disclosed |