Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 2/20 | 0.38 |
| ▸ | NAAA | Q02083 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9393815 | 0.78 | ALDH1A1 (0.47) | ALDH1A1ATMNAAATSHRHPGD | |
| SCHEMBL7491334 | 0.78 | ALDH1A1 (0.47) | ALDH1A1ATMNAAATSHRHPGD | |
| SCHEMBL28009595 | 0.75 | ALDH1A1 (0.44) | ALDH1A1ATMNAAATSHRHPGD | |
| SCHEMBL2761758 | 0.75 | ALDH1A1 (0.44) | ALDH1A1ATMNAAATSHRHPGD | |
| SCHEMBL7373318 | 0.75 | ALDH1A1 (0.44) | ALDH1A1ATMNAAATSHRHPGD | |
| SCHEMBL40274 | 0.74 | ALDH1A1 (0.61) | ALDH1A1ATMNAAATSHRHPGD | |
| SCHEMBL8961566 | 0.74 | ALDH1A1 (0.47) | ALDH1A1ATMNAAATSHRHPGD | |
| Hydrochloric Acid SCHEMBL7703133 | 0.73 | ALDH1A1 (0.42) | ALDH1A1ATMNAAATSHRHPGD | |
| SCHEMBL6259632 | 0.73 | ALDH1A1 (0.42) | ALDH1A1ATMNAAATSHRHPGD | |
| Hydrochloric Acid SCHEMBL7377199 | 0.73 | ALDH1A1 (0.42) | ALDH1A1ATMNAAATSHRHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0740655-A1 | METALLOPROTEINASE INHIBITORS | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 1996-11-06 | — | — | EP | disclosed |
| WO-1995019961-A1 | METALLOPROTEINASE INHIBITORS | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 1995-07-27 | — | — | WO | disclosed |