Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN5A | Q14524 | 2/20 | 0.44 |
| ▸ | HTR2A | P28223 | 6/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 6/20 | 0.42 |
| ▸ | HRH1 | P35367 | 6/20 | 0.42 |
| ▸ | DRD3 | P35462 | 6/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 6/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.42 |
| ▸ | HTR6 | P50406 | 5/20 | 0.42 |
| ▸ | CACNA1C | Q13936 | 5/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 5/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 5/20 | 0.42 |
| ▸ | CACNA1F | O60840 | 4/20 | 0.42 |
| ▸ | DRD4 | P21917 | 4/20 | 0.42 |
| ▸ | HRH2 | P25021 | 4/20 | 0.42 |
| ▸ | CACNA1D | Q01668 | 4/20 | 0.42 |
| ▸ | CACNA1S | Q13698 | 4/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.42 |
| ▸ | DRD5 | P21918 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9010739 | 0.95 | SLC18A3 (0.44) | SCN5AHTR2AADRA1AHRH1DRD3 | |
| SCHEMBL8989703 | 0.89 | SLC18A3 (0.47) | DRD3DRD2LMNACYP1A2KDM4E | |
| SCHEMBL7779086 | 0.85 | SLC18A3 (0.56) | DRD3SLC6A3HTR1ADRD2CYP1A2 | |
| SCHEMBL7781788 | 0.85 | SLC18A3 (0.50) | DRD3SLC6A3HTR1ADRD2CYP1A2 | |
| SCHEMBL8989705 | 0.83 | SLC18A3 (0.43) | DRD3DRD2LMNACYP1A2KDM4E | |
| SCHEMBL8989738 | 0.82 | SLC18A3 (0.42) | DRD3DRD2LMNACYP1A2KDM4E | |
| SCHEMBL7781178 | 0.81 | KDM1A (0.45) | SCN5AHTR2AHRH1DRD3DRD4 | |
| SCHEMBL8989718 | 0.80 | KDM1A (0.39) | HTR2ASLC6A3DRD4HTR2CDRD2 | |
| SCHEMBL7480872 | 0.80 | KDM1A (0.39) | HTR2ASLC6A3DRD4HTR2CDRD2 | |
| SCHEMBL7073067 | 0.80 | KDM1A (0.39) | HTR2ASLC6A3DRD4HTR2CDRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0646110-B1 | N-SUBSTITUTED 3-AZABICYCLO[3.2.0]HEPTANE DERIVATIVES USEFUL AS NEUROLEPTIC AGENTS | BASF AG (DE) | 1996-10-23 | — | — | EP | disclosed |