Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 6/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 6/20 | 0.43 |
| ▸ | HRH1 | P35367 | 6/20 | 0.43 |
| ▸ | DRD3 | P35462 | 6/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 6/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 5/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.43 |
| ▸ | HTR6 | P50406 | 5/20 | 0.43 |
| ▸ | CACNA1C | Q13936 | 5/20 | 0.43 |
| ▸ | HTR2C | P28335 | 4/20 | 0.43 |
| ▸ | CACNA1F | O60840 | 4/20 | 0.43 |
| ▸ | DRD4 | P21917 | 4/20 | 0.43 |
| ▸ | HRH2 | P25021 | 4/20 | 0.43 |
| ▸ | CACNA1D | Q01668 | 4/20 | 0.43 |
| ▸ | CACNA1S | Q13698 | 4/20 | 0.43 |
| ▸ | DRD5 | P21918 | 3/20 | 0.43 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.43 |
| ▸ | HTR7 | P34969 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9010705 | 0.95 | SCN5A (0.44) | SLC18A3HTR2AADRA1AHRH1DRD3 | |
| SCHEMBL7779086 | 0.91 | SLC18A3 (0.56) | SLC18A3DRD3SLC6A3DRD2CYP1A2 | |
| SCHEMBL7781788 | 0.86 | SLC18A3 (0.50) | SLC18A3DRD3SLC6A3DRD2CYP1A2 | |
| SCHEMBL8989703 | 0.84 | SLC18A3 (0.47) | SLC18A3DRD3DRD2LMNACYP1A2 | |
| SCHEMBL7781274 | 0.83 | HTR2A (0.45) | HTR2AHRH1DRD3DRD4DRD5 | |
| SCHEMBL8989700 | 0.81 | GRIN2B (0.45) | SLC18A3HTR2AADRA1AHRH1DRD3 | |
| SCHEMBL7071917 | 0.80 | KDM1A (0.51) | HTR2AHRH1DRD3SLC6A3HTR6 | |
| SCHEMBL7781094 | 0.79 | DRD2 (0.60) | SLC18A3HTR2AADRA1AHRH1DRD3 | |
| SCHEMBL8989705 | 0.79 | SLC18A3 (0.43) | SLC18A3DRD3DRD2LMNACYP1A2 | |
| SCHEMBL8989732 | 0.79 | PRCP (0.44) | SLC6A3DRD2SLC6A4SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0646110-B1 | N-SUBSTITUTED 3-AZABICYCLO[3.2.0]HEPTANE DERIVATIVES USEFUL AS NEUROLEPTIC AGENTS | BASF AG (DE) | 1996-10-23 | — | — | EP | disclosed |
| EP-0646110-A1 | N-SUBSTITUED 3-AZABICYCLO 3.2.0]HEPTANE DERIVATIVES USEFUL AS NEUROLEPTIC AGENTS ETC. | BASF AG (DE) | 1995-04-05 | — | — | EP | disclosed |
| WO-1994000431-A1 | N-SUBSTITUED 3-AZABICYCLO[3.2.0]HEPTANE DERIVATIVES USEFUL AS NEUROLEPTIC AGENTS ETC. | BASF AKTIENGESELLSCHAFT (DE) | 1994-01-06 | — | — | WO | disclosed |