SCHEMBL9010768

SCHEMBL9010768

CN1CC2CC(c3ccccc3)C2C1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRNA7 P36544 1/20 0.42
KDM1A O60341 6/20 0.41
MAOB P27338 8/20 0.41
MAOA P21397 7/20 0.41
CYP2C19 P33261 4/20 0.41
CYP2B6 P20813 3/20 0.41
CYP1A2 P05177 2/20 0.41
CYP2D6 P10635 2/20 0.41
CYP2C9 P11712 2/20 0.41
LMNA P02545 2/20 0.41
TAAR1 Q96RJ0 2/20 0.41
CYP3A4 P08684 1/20 0.41
HTR1A P08908 1/20 0.41
ADRA2A P08913 1/20 0.41
CYP2A6 P11509 1/20 0.41
SLC6A2 P23975 1/20 0.41
HTR2C P28335 1/20 0.41
ADRA1A P35348 1/20 0.41
DRD3 P35462 1/20 0.41
SLC6A3 Q01959 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9090924 0.84 CHRNA7 (0.44) CHRNA7KDM1ACYP2D6SLC6A2SLC6A3
SCHEMBL8989697 0.82 KDM1A (0.44) KDM1ASLC6A2HTR2CSLC6A3
SCHEMBL12539573 0.82 KDM1A (0.44) KDM1ASLC6A2HTR2CSLC6A3
SCHEMBL8541943 0.81 CHRNA7 (0.42) CHRNA7KDM1ASLC6A2SLC6A3MEN1
SCHEMBL8541939 0.81 CHRNA7 (0.42) CHRNA7KDM1ASLC6A2SLC6A3MEN1
SCHEMBL8900770 0.81 MEN1 (0.44) CHRNA7KDM1ASLC6A2SLC6A3MEN1
SCHEMBL8546489 0.81 CHRNA7 (0.42) CHRNA7KDM1ASLC6A2SLC6A3MEN1
SCHEMBL8967406 0.81 CHRNA7 (0.42) CHRNA7KDM1ASLC6A2SLC6A3MEN1
SCHEMBL12539570 0.80 HTR2A (0.45) MAOBMAOACYP2D6LMNASLC6A2
SCHEMBL8967765 0.79 CHRNA7 (0.46) CHRNA7KDM1ASLC6A2SLC6A3MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0646110-B1 N-SUBSTITUTED 3-AZABICYCLO[3.2.0]HEPTANE DERIVATIVES USEFUL AS NEUROLEPTIC AGENTS BASF AG (DE) 1996-10-23 EP disclosed
EP-0646110-A1 N-SUBSTITUED 3-AZABICYCLO 3.2.0]HEPTANE DERIVATIVES USEFUL AS NEUROLEPTIC AGENTS ETC. BASF AG (DE) 1995-04-05 EP disclosed
WO-1994000431-A1 N-SUBSTITUED 3-AZABICYCLO[3.2.0]HEPTANE DERIVATIVES USEFUL AS NEUROLEPTIC AGENTS ETC. BASF AKTIENGESELLSCHAFT (DE) 1994-01-06 WO disclosed