Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.43 |
| ▸ | GUSB | P08236 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | MGAM | O43451 | 2/20 | 0.42 |
| ▸ | SI | P14410 | 2/20 | 0.42 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.41 |
| ▸ | VDR | P11473 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7669897 | 0.87 | PDE2A (0.60) | PDE2AHSD17B10PKMABCG2GUSB | |
| SCHEMBL7672854 | 0.80 | KDM4E (0.50) | PDE2AHSD17B10PKMABCG2GUSB | |
| SCHEMBL3722376 | 0.76 | PDE5A (0.58) | ABCG2GUSBKDM4EALDH1A1HPGD | |
| SCHEMBL7673043 | 0.73 | KDM4E (0.64) | HSD17B10PKMABCG2GUSBGAA | |
| SCHEMBL38652457 | 0.73 | KDM4E (0.64) | HSD17B10PKMABCG2GUSBGAA | |
| SCHEMBL14876999 | 0.73 | ABCG2 (0.53) | HSD17B10ABCG2KDM4EALDH1A1HPGD | |
| SCHEMBL7668615 | 0.73 | NR1I2 (0.72) | HSD17B10KDM4EALDH1A1HPGDKMT2A | |
| SCHEMBL7669296 | 0.72 | NR1I2 (0.56) | HSD17B10PKMABCG2GUSBKDM4E | |
| SCHEMBL14876858 | 0.72 | ABCG2 (0.52) | HSD17B10ABCG2GUSBKDM4EALDH1A1 | |
| SCHEMBL10628266 | 0.70 | PDE5A (0.42) | PDE2AABCG2GUSBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0641351-B1 | ENZYMATIC ANALYSIS USING SUBSTRATES THAT YIELD FLUORESCENT PRECIPITATES | MOLECULAR PROBES INC (US) | 1996-10-23 | — | — | EP | disclosed |
| US-5443986-A | Enzymatic analysis using substrates that yield fluorescent precipitates | MOLECULAR PROBES, INC. (US) | 1995-08-22 | — | — | US | disclosed |
| EP-0641351-A1 | ENZYMATIC ANALYSIS USING SUBSTRATES THAT YIELD FLUORESCENT PRECIPITATES. | MOLECULAR PROBES INC (US) | 1995-03-08 | — | — | EP | disclosed |
| US-5316906-A | Fluorescent dyes for substrates | MOLECULAR PROBES, INC. (US) | 1994-05-31 | — | — | US | disclosed |
| WO-1993004077-A1 | ENZYMATIC ANALYSIS USING SUBSTRATES THAT YIELD FLUORESCENT PRECIPITATES | MOLECULAR PROBES, INC. (US) | 1993-03-04 | — | — | WO | disclosed |