Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 2/20 | 0.30 |
| ▸ | CA1 | P00915 | 2/20 | 0.30 |
| ▸ | CA2 | P00918 | 2/20 | 0.30 |
| ▸ | CDK1 | P06493 | 2/20 | 0.30 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.30 |
| ▸ | CDK2 | P24941 | 2/20 | 0.30 |
| ▸ | CA9 | Q16790 | 2/20 | 0.30 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.30 |
| ▸ | CDK4 | P11802 | 1/20 | 0.30 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.30 |
| ▸ | CCND1 | P24385 | 1/20 | 0.30 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9010846 | 0.88 | DAO (0.33) | DAOMEN1KMT2ACA12CA1 | |
| SCHEMBL79535 | 0.78 | DAO (0.32) | DAO | |
| SCHEMBL79536 | 0.76 | DAO (0.33) | DAO | |
| SCHEMBL29377568 | 0.76 | DAO (0.31) | DAO | |
| SCHEMBL4084854 | 0.72 | TDP1 (0.38) | MEN1KMT2AALDH1A1MAPTCA12 | |
| SCHEMBL9441965 | 0.71 | RHEB (0.33) | DAOMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL4084856 | 0.70 | CA2 (0.36) | ALDH1A1GAAMAPTHPGDCA12 | |
| SCHEMBL27788007 | 0.69 | AR (0.40) | DAOMEN1KMT2AALDH1A1GAA | |
| SCHEMBL19332262 | 0.67 | CYP1A2 (0.44) | ALDH1A1GAAHPGD | |
| SCHEMBL1843064 | 0.67 | SLC22A6 (0.34) | CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0641351-B1 | ENZYMATIC ANALYSIS USING SUBSTRATES THAT YIELD FLUORESCENT PRECIPITATES | MOLECULAR PROBES INC (US) | 1996-10-23 | — | — | EP | disclosed |
| US-5443986-A | Enzymatic analysis using substrates that yield fluorescent precipitates | MOLECULAR PROBES, INC. (US) | 1995-08-22 | — | — | US | disclosed |
| EP-0641351-A1 | ENZYMATIC ANALYSIS USING SUBSTRATES THAT YIELD FLUORESCENT PRECIPITATES. | MOLECULAR PROBES INC (US) | 1995-03-08 | — | — | EP | disclosed |
| US-5316906-A | Fluorescent dyes for substrates | MOLECULAR PROBES, INC. (US) | 1994-05-31 | — | — | US | disclosed |
| WO-1993004077-A1 | ENZYMATIC ANALYSIS USING SUBSTRATES THAT YIELD FLUORESCENT PRECIPITATES | MOLECULAR PROBES, INC. (US) | 1993-03-04 | — | — | WO | disclosed |