Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.33 |
| ▸ | HTR2A | P28223 | 4/20 | 0.32 |
| ▸ | HTR2C | P28335 | 2/20 | 0.32 |
| ▸ | HTR2B | P41595 | 2/20 | 0.32 |
| ▸ | ATM | Q13315 | 2/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.31 |
| ▸ | PDE2A | O00408 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL900763 | 0.87 | HTR2A (0.35) | HTR2AHTR2CHTR2BSLC6A2SLC6A4 | |
| SCHEMBL12474346 | 0.77 | IDO1 (0.35) | IDO1HTR2AHTR2CHTR2BATM | |
| SCHEMBL12474332 | 0.73 | KDM4E (0.36) | KDM4E | |
| SCHEMBL12474312 | 0.73 | FFAR4 (0.35) | L3MBTL1PDE2A | |
| SCHEMBL900575 | 0.72 | IDO1 (0.32) | IDO1HTR2AHTR2CHTR2B | |
| SCHEMBL17887542 | 0.72 | RIPK1 (0.41) | IDO1ATMSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL900207 | 0.71 | SMN1; SMN2 (0.34) | HTR2AHTR2CHTR2BKDM4EPDE2A | |
| SCHEMBL12474343 | 0.70 | KDM4E (0.36) | KDM4E | |
| SCHEMBL12474301 | 0.70 | PDE2A (0.41) | HTR2AHTR2CHTR2BPDE2A | |
| SCHEMBL900986 | 0.70 | PDE2A (0.33) | HTR2AHTR2CHTR2BPDE2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2621922-A1 | A PROCESS FOR THE SYNTHESIS OF THIO-TRIAZOLO-GROUP CONTAINING COMPOUNDS | BASF SE (DE) | 2013-08-07 | — | — | EP | disclosed |
| WO-2012041858-A1 | A PROCESS FOR THE SYNTHESIS OF THIO-TRIAZOLO-GROUP CONTAINING COMPOUNDS | BASF SE (DE) | 2012-04-05 | — | — | WO | disclosed |