Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | DRD4 | P21917 | 3/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.49 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.48 |
| ▸ | CTSB | P07858 | 1/20 | 0.48 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9010996 | 0.89 | NPC1 (0.56) | NPC1RAB9ADRD4TSHRLMNA | |
| SCHEMBL9011267 | 0.83 | DRD4 (0.60) | NPC1RAB9ADRD4TSHRLMNA | |
| SCHEMBL7811611 | 0.82 | NPC1 (0.56) | NPC1RAB9ADRD4TSHRLMNA | |
| SCHEMBL7811589 | 0.81 | DRD4 (0.55) | NPC1RAB9ADRD4TSHRLMNA | |
| SCHEMBL9011113 | 0.79 | ALDH1A1 (0.53) | TSHRLMNAFFAR1USP2ALDH1A1 | |
| SCHEMBL9011091 | 0.79 | TSHR (0.57) | NPC1RAB9ADRD4TSHRLMNA | |
| SCHEMBL9010973 | 0.78 | DRD4 (0.63) | NPC1RAB9ADRD4TSHRLMNA | |
| SCHEMBL2618041 | 0.76 | NPC1 (0.72) | NPC1RAB9ADRD4TSHRLMNA | |
| SCHEMBL9011013 | 0.76 | TSHR (0.51) | NPC1RAB9ADRD4TSHRLMNA | |
| SCHEMBL7302754 | 0.76 | NPC1 (0.72) | NPC1RAB9ADRD4TSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1035178-C | Arylamide derivatives | SS PHARMACEUTICAL CO (JP) | 1997-06-18 | — | — | CN | disclosed |
| US-5532371-A | SIDE EFFECT REDUCTION | SS PHARMACEUTICAL CO., LTD. (JP) | 1996-07-02 | — | — | US | disclosed |
| US-5411972-A | Arylamide derivatives for treating hyperlipemia | SS PHARMACEUTICAL CO., LTD. (JP) | 1995-05-02 | — | — | US | disclosed |
| EP-0607536-A1 | Arylamide derivatives | SS PHARMACEUTICAL CO., LTD. (JP) | 1994-07-27 | — | — | EP | disclosed |