Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.54 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.53 |
| ▸ | CHRM2 | P08172 | 6/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9010986 | 0.85 | AVPR1A (0.56) | ALDH1A1MEN1KMT2AKDM4EHIF1A | |
| SCHEMBL7813350 | 0.84 | ALDH1A1 (0.52) | ALDH1A1MEN1KMT2AKDM4EHIF1A | |
| SCHEMBL9011113 | 0.82 | ALDH1A1 (0.53) | ALDH1A1MEN1KMT2AKDM4EHIF1A | |
| SCHEMBL9011267 | 0.81 | DRD4 (0.60) | ALDH1A1CHRM2LMNATSHR | |
| SCHEMBL9011033 | 0.80 | AVPR1A (0.55) | ALDH1A1MEN1KMT2AAVPR1ALMNA | |
| SCHEMBL7817608 | 0.79 | ALDH1A1 (0.50) | ALDH1A1MEN1KMT2AKDM4EHIF1A | |
| SCHEMBL9011215 | 0.78 | AVPR1A (0.53) | ALDH1A1MEN1KMT2AKDM4EHIF1A | |
| SCHEMBL7242072 | 0.77 | CYP2C9 (0.68) | ALDH1A1AVPR1ACHRM2LMNA | |
| SCHEMBL9011074 | 0.76 | ALDH1A1 (0.51) | ALDH1A1MEN1KMT2AKDM4EHIF1A | |
| SCHEMBL15014095 | 0.74 | ALDH1A1 (0.57) | ALDH1A1MEN1KMT2AKDM4EHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5532371-A | SIDE EFFECT REDUCTION | SS PHARMACEUTICAL CO., LTD. (JP) | 1996-07-02 | — | — | US | disclosed |
| US-5411972-A | Arylamide derivatives for treating hyperlipemia | SS PHARMACEUTICAL CO., LTD. (JP) | 1995-05-02 | — | — | US | disclosed |
| EP-0607536-A1 | Arylamide derivatives | SS PHARMACEUTICAL CO., LTD. (JP) | 1994-07-27 | — | — | EP | disclosed |