Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 3/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.63 |
| ▸ | RAB9A | P51151 | 4/20 | 0.63 |
| ▸ | MEN1 | O00255 | 3/20 | 0.63 |
| ▸ | NPC1 | O15118 | 2/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | PTAFR | P25105 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.50 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15592299 | 0.84 | CYP1A2 (0.66) | EPHX2KMT2ARAB9AMEN1SMN1; SMN2 | |
| SCHEMBL62325 | 0.84 | EPHX2 (0.72) | EPHX2KMT2ARAB9AMEN1NPC1 | |
| SCHEMBL2227019 | 0.82 | KMT2A (0.65) | EPHX2KMT2ARAB9AMEN1NPC1 | |
| SCHEMBL4182430 | 0.81 | EPHX2 (1.00) | EPHX2KMT2ARAB9AMEN1NPC1 | |
| SCHEMBL678984 | 0.81 | EPHX2 (0.70) | EPHX2KMT2ARAB9AMEN1NPC1 | |
| SCHEMBL29560373 | 0.81 | EPHX2 (0.70) | EPHX2KMT2ARAB9AMEN1NPC1 | |
| SCHEMBL5553310 | 0.80 | EPHX2 (0.92) | EPHX2KMT2ARAB9AMEN1NPC1 | |
| SCHEMBL27441071 | 0.79 | PRSS1 (0.69) | KMT2ARAB9AMEN1NPC1SMN1; SMN2 | |
| SCHEMBL17822214 | 0.79 | EPHX2 (0.75) | EPHX2KMT2ARAB9AMEN1NPC1 | |
| SCHEMBL9809561 | 0.79 | RAB9A (0.76) | EPHX2KMT2ARAB9AMEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5525727-A | ANALGESIC OR NARCOTIC ANTAGONIST | UNIVERSITY OF FLORIDA (US) | 1996-06-11 | — | — | US | disclosed |
| US-5008257-A | Penicillin or cephalosporin antibiotics | UNIVERSITY OF FLORIDA (US) | 1991-04-16 | — | — | US | disclosed |
| US-4900837-A | Brain-specific drug delivery of steroid sex hormones cleaved from pyridinium carboxylates and dihydro-pyridine carboxylate precursors | UNIVERSITY OF FLORIDA (US) | 1990-02-13 | — | — | US | disclosed |
| US-4880921-A | Brain-specific drug delivery | UNIVERSITY OF FLORIDA (US) | 1989-11-14 | — | — | US | disclosed |
| US-4824850-A | DIHYDROPYRIDINE-PYRIDINIUM SALT REDOX CARRIER | UNIVERSITY OF FLORIDA (US) | 1989-04-25 | — | — | US | disclosed |
| US-4786647-A | DIHYDROPYRIDINE DERIVATIVES OF AMINOBUTYRIC ACID | UNIVERSITY OF FLORIDA (US) | 1988-11-22 | — | — | US | disclosed |