Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 10/20 | 0.56 |
| ▸ | HRH1 | P35367 | 5/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.54 |
| ▸ | DRD2 | P14416 | 4/20 | 0.54 |
| ▸ | ADRA2B | P18089 | 4/20 | 0.54 |
| ▸ | ADRA2C | P18825 | 4/20 | 0.54 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.54 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.54 |
| ▸ | HTR2A | P28223 | 4/20 | 0.54 |
| ▸ | HTR2C | P28335 | 4/20 | 0.54 |
| ▸ | ADRA1A | P35348 | 4/20 | 0.54 |
| ▸ | DRD3 | P35462 | 4/20 | 0.54 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.54 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.54 |
| ▸ | SLC22A1 | O15245 | 3/20 | 0.54 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8728836 | 0.86 | SLC6A4 (0.52) | SLC6A4HRH1MAPTCHRM1DRD2 | |
| SCHEMBL8728526 | 0.82 | SLC6A4 (0.50) | SLC6A4HRH1MAPTCHRM1DRD2 | |
| SCHEMBL26967791 | 0.78 | SLC6A4 (0.69) | SLC6A4HRH1MAPTCHRM1DRD2 | |
| SCHEMBL9763463 | 0.76 | HTT (0.56) | MAPTLMNAALDH1A1KDM4EHSD17B10 | |
| SCHEMBL9490693 | 0.75 | SLC6A4 (0.72) | SLC6A4HRH1MAPTCHRM1DRD2 | |
| SCHEMBL221187 | 0.75 | SLC6A4 (0.68) | SLC6A4HRH1MAPTCHRM1DRD2 | |
| SCHEMBL13040622 | 0.74 | SLC6A4 (0.63) | SLC6A4HRH1MAPTCHRM1DRD2 | |
| SCHEMBL218473 | 0.74 | SLC6A4 (0.66) | SLC6A4HRH1MAPTCHRM1DRD2 | |
| SCHEMBL9011097 | 0.73 | SLC6A4 (0.56) | SLC6A4HRH1MAPTCHRM1DRD2 | |
| Imipramine SCHEMBL20644144 | 0.73 | SLC6A4 (0.83) | SLC6A4HRH1MAPTCHRM1DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5525727-A | ANALGESIC OR NARCOTIC ANTAGONIST | UNIVERSITY OF FLORIDA (US) | 1996-06-11 | — | — | US | disclosed |
| US-5187158-A | Sustained delivery of viricides | UNIVERSITY OF FLORIDA (US) | 1993-02-16 | — | — | US | disclosed |
| US-5008257-A | Penicillin or cephalosporin antibiotics | UNIVERSITY OF FLORIDA (US) | 1991-04-16 | — | — | US | disclosed |
| US-4900837-A | Brain-specific drug delivery of steroid sex hormones cleaved from pyridinium carboxylates and dihydro-pyridine carboxylate precursors | UNIVERSITY OF FLORIDA (US) | 1990-02-13 | — | — | US | disclosed |
| US-4880921-A | Brain-specific drug delivery | UNIVERSITY OF FLORIDA (US) | 1989-11-14 | — | — | US | disclosed |
| US-4824850-A | DIHYDROPYRIDINE-PYRIDINIUM SALT REDOX CARRIER | UNIVERSITY OF FLORIDA (US) | 1989-04-25 | — | — | US | disclosed |